6-bromo-5-methyl-1H-imidazo[4,5-b]pyridine

Base Information

• Chemical Name: 6-bromo-5-methyl-1H-imidazo[4,5-b]pyridine
• CAS No.: 28279-41-6
• Molecular Formula: C7H6 Br N3
• Molecular Weight: 212.049
• Hs Code.: 2933990090
• European Community (EC) Number: 248-936-0
• DSSTox Substance ID: DTXSID7067372
• Nikkaji Number: J250.688B
• ChEMBL ID: CHEMBL1725708
• Mol file: 28279-41-6.mol

Synonyms:6-bromo-5-methyl-1H-imidazo[4,5-b]pyridine;28279-41-6;6-BROMO-5-METHYL-3H-IMIDAZO[4,5-b]PYRIDINE;6-Bromo-5-methylimidazo[4,5-b]pyridine;C7H6BrN3;1H-Imidazo[4,5-b]pyridine, 6-bromo-5-methyl-;EINECS 248-936-0;6-Bromo-5-methyl-4-azabenzimidazole;6-Bromo-5-methylimidazo(4,5-b)pyridine;1H-Imidazo(4,5-b)pyridine, 6-bromo-5-methyl-;3H-Imidazo(4,5-b)pyridine, 6-bromo-5-methyl-;6-Bromo-5-methyl-1H-imidazo(4,5-b)pyridine;Cambridge id 5709473;Cambridge id 5722012;MLS000108063;C7-H6-Br-N3;SCHEMBL3047163;CHEMBL1725708;DTXSID7067372;HMS2186K06;CCG-15087;MFCD00184166;STK865207;AKOS000269715;AKOS005208497;BP-10279;DS-17354;SMR000104026;BB 0241022;CS-0187190;EU-0033435;FT-0724995;C74456;EN300-110854;AB00094316-01;A913511;SR-01000389059;SR-01000389059-1;F0266-2227;F1791-0299;Z277557456;6-Bromo-5-methyl-3H-imidazo(4,5-b)pyridine, AldrichCPR

Chemical Property of 6-bromo-5-methyl-1H-imidazo[4,5-b]pyridine

Chemical Property:

• Vapor Pressure: 3.95E-06mmHg at 25°C
• Boiling Point: 396.3°Cat760mmHg
• Flash Point: 193.5°C
• PSA: 41.57000
• Density: 1.755g/cm³
• LogP: 2.02880
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 210.97451
• Heavy Atom Count: 11
• Complexity: 153

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-5-methyl-3h-imidazo[4,5-b]pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=C2C(=N1)N=CN2)Br

Technology Process of 6-bromo-5-methyl-1H-imidazo[4,5-b]pyridine

There total 6 articles about 6-bromo-5-methyl-1H-imidazo[4,5-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.5%

2,3-diamino-5-bromo-6-methylpyridine (59352-90-8) + n-pentyl formate (638-49-3) → 6-bromo-5-methylimidazo[4,5-b]pyridine (28279-41-6)

Guidance literature:

at 170 - 180 ℃; for 4h;

DOI:10.1007/s11167-005-0392-y

Reference yield:

5-bromo-6-methyl-pyridin-2-ylamine (42753-71-9) → 6-bromo-5-methylimidazo[4,5-b]pyridine (28279-41-6)

Guidance literature:

Multi-step reaction with 3 steps

1: HNO₃; H₂SO₄ / 0 - 60 °C

2: 90 percent / hydrazine hydrate; Zn / butan-1-ol / Heating

3: 90.5 percent / 4 h / 170 - 180 °C

With sulfuric acid; nitric acid; hydrazine hydrate; zinc; In butan-1-ol;

DOI:10.1007/s11167-005-0392-y

Reference yield:

2-amino-5-bromo-6-methyl-3-nitropyridine (68957-50-6) → 6-bromo-5-methylimidazo[4,5-b]pyridine (28279-41-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / hydrazine hydrate; Zn / butan-1-ol / Heating

2: 90.5 percent / 4 h / 170 - 180 °C

With hydrazine hydrate; zinc; In butan-1-ol;

DOI:10.1007/s11167-005-0392-y

upstream raw materials:

formic acid

2,3-diamino-5-bromo-6-methylpyridine

n-pentyl formate

2-Amino-6-methylpyridine

Downstream raw materials:

5-methylpyridol[2,3-d]imidazole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 28279-41-6 6-bromo-5-methyl-1H-imidazo[4,5-b]pyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send