5-((Dimethylamino)methyl)quinolin-8-ol

Base Information

Chemical Name:5-((Dimethylamino)methyl)quinolin-8-ol
CAS No.:7545-62-2
Molecular Formula:C12H14N2O
Molecular Weight:202.25236
Hs Code.:2933499090
ChEMBL ID:CHEMBL3251397
DSSTox Substance ID:DTXSID10408513
Mol file:7545-62-2.mol

Synonyms:5-((Dimethylamino)methyl)quinolin-8-ol;7545-62-2;5-[(dimethylamino)methyl]quinolin-8-ol;CHEMBL3251397;DTXSID10408513;AKOS002717874;SB70346

Suppliers and Price of 5-((Dimethylamino)methyl)quinolin-8-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
5-((dimethylamino)methyl)quinolin-8-ol 95%
1g
$ 888.00

American Custom Chemicals Corporation
5-((DIMETHYLAMINO)METHYL)QUINOLIN-8-OL 95.00%
5MG
$ 501.52

Alichem
5-((Dimethylamino)methyl)quinolin-8-ol
1g
$ 978.50

Total 5 raw suppliers

Chemical Property of 5-((Dimethylamino)methyl)quinolin-8-ol

Chemical Property:

Boiling Point:347.6±27.0 °C(Predicted)
PKA:3.99±0.10(Predicted)
PSA：36.36000
Density:1.177±0.06 g/cm3(Predicted)
LogP:2.00200
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:202.110613074
Heavy Atom Count:15
Complexity:208

Purity/Quality:

95+% ^*data from raw suppliers

5-((dimethylamino)methyl)quinolin-8-ol 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CC1=C2C=CC=NC2=C(C=C1)O

Technology Process of 5-((Dimethylamino)methyl)quinolin-8-ol

There total 4 articles about 5-((Dimethylamino)methyl)quinolin-8-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 506-59-2
N,N-dimethylammonium chloride

: 4053-45-6
5-chloromethyl-8-hydroxyquinoline hydrochloride

: 7545-62-2
5-dimethylaminomethyl-quinolin-8-ol

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 0.416667h;
DOI:10.3390/molecules13040922

Reference yield:

: 4053-45-6
5-chloromethyl-8-hydroxyquinoline hydrochloride

: 124-40-3
dimethyl amine

: 7545-62-2
5-dimethylaminomethyl-quinolin-8-ol

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.3390/12051191

Reference yield:

: 148-24-3,24804-14-6
8-quinolinol

: 7545-62-2
5-dimethylaminomethyl-quinolin-8-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / aq. HCl / 8 h / 50 °C

2: triethylamine / CH₂Cl₂ / 20 °C

With hydrogenchloride; triethylamine; In dichloromethane;
DOI:10.3390/12051191