6-ETHOXY-2-TETRALONE

Base Information

• Chemical Name: 6-ETHOXY-2-TETRALONE
• CAS No.: 69788-78-9
• Molecular Formula: C12H14O2
• Molecular Weight: 0
• Mol file: 69788-78-9.mol

Synonyms:6-ETHOXY-2-TETRALONE

Chemical Property of 6-ETHOXY-2-TETRALONE

Chemical Property:

• PSA: 26.30000
• LogP: 2.14310

Purity/Quality:

6-ETHOXY-2-TETRALONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-ETHOXY-2-TETRALONE

There total 4 articles about 6-ETHOXY-2-TETRALONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethene (74-85-1) + 4-ethoxyphenylacetic acid chloride (10368-35-1) → 6-ethoxy-3,4-dihydro-2(1H)-naphthalenone (69788-78-9)

Guidance literature:

With aluminium trichloride; In dichloromethane; for 4h; Ambient temperature;

DOI:10.1021/jm00353a016

Reference yield:

4-ethoxyphenylacetic acid chloride (10368-35-1) → 6-ethoxy-3,4-dihydro-2(1H)-naphthalenone (69788-78-9)

Guidance literature:

aluminium trichloride; In ice-water; dichloromethane;

Reference yield:

4-ethoxyphenylacetic acid (4919-33-9) → 6-ethoxy-3,4-dihydro-2(1H)-naphthalenone (69788-78-9)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅ / CH₂Cl₂

2: 100 percent / AlCl₃ / CH₂Cl₂ / 4 h / Ambient temperature

With aluminium trichloride; phosphorus pentachloride; In dichloromethane;

DOI:10.1021/jm00353a016

upstream raw materials:

ethene

4-ethoxyphenylacetic acid chloride

4-ethoxyphenylacetic acid

Downstream raw materials:

3,4-Dimethoxy-benzoic acid 4-[(6-ethoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-ethyl-amino]-butyl ester

Refernces

• 1、 Kanao, Munefumi,Hashizume, Takeshi,Ichikawa, Yoshifumi,Irie, Kiyoshi,Isoda, Sumiro. "Spasmolytic Agents. 2. 1,2,3,4-Tetrahydro-2-naphthylamine Derivatives". . p. 1358 - 1363. Retrieved 2007/10/02.