1-(boc-aMino)-1-(4-chlorophenyl)-cyclobutane

Base Information

• Chemical Name: 1-(boc-aMino)-1-(4-chlorophenyl)-cyclobutane
• CAS No.: 1032349-96-4
• Molecular Formula: C15H20ClNO2
• Molecular Weight: 281.782
• Hs Code.: 2921499090
• Mol file: 1032349-96-4.mol

Synonyms:1-(boc-aMino)-1-(4-chlorophenyl)-cyclobutane;tert-butyl 1-(4-chlorophenyl)cyclobutylcarbamate

Chemical Property of 1-(boc-aMino)-1-(4-chlorophenyl)-cyclobutane

Chemical Property:

• Boiling Point: 386.3±31.0 °C(Predicted)
• PKA: 11.82±0.20(Predicted)
• PSA: 41.82000
• Density: 1.16±0.1 g/cm3(Predicted)
• LogP: 4.44830

Purity/Quality:

97% ^*data from raw suppliers

1-(Boc-amino)-1-(4-chlorophenyl)-cyclobutane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(boc-aMino)-1-(4-chlorophenyl)-cyclobutane

There total 1 articles about 1-(boc-aMino)-1-(4-chlorophenyl)-cyclobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + 1-(4-chlorophenyl)cyclobutane-1-carboxylic acid (50921-39-6) → tert-butyl [1-(4-chlorophenyl)cyclobutyl]carbamate (1032349-96-4)

Guidance literature:

With sodium azide; tetrabutylammomium bromide; zinc trifluoromethanesulfonate; In tetrahydrofuran; at 60 ℃; for 18h;

Reference yield: 61.0%

zinc(II) cyanide (557-21-1) + tert-butyl [1-(4-chlorophenyl)cyclobutyl]carbamate (1032349-96-4) → tert-butyl[1-(4-cyanophenyl)cyclobutyl]carbamate (1032349-97-5)

Guidance literature:

With bis(tri-t-butylphosphine)palladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 4h; Inert atmosphere;

DOI:10.1021/jm201394e

Reference yield:

tert-butyl [1-(4-chlorophenyl)cyclobutyl]carbamate (1032349-96-4) + bis(pinacol)diborane (73183-34-3) → {1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclobutyl}-carbamic acid tert.-butyl ester (1032528-06-5)

Guidance literature:

With potassium acetate; bis(tri-tert-butylphosphine)palladium⁽⁰⁾; In 1,4-dioxane; at 80 ℃; for 46h;

upstream raw materials:

di-tert-butyl dicarbonate

1-(4-chlorophenyl)cyclobutane-1-carboxylic acid

Downstream raw materials:

{1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclobutyl}-carbamic acid tert.-butyl ester

tert-butyl[1-(4-cyanophenyl)cyclobutyl]carbamate

tert-butyl 1-(4-(2-phenylacetyl)phenyl)cyclobutylcarbamate

tert-butyl 1-(4-(2-bromo-2-phenylacetyl)phenyl)cyclobutylcarbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1032349-96-4 1-(boc-aMino)-1-(4-chlorophenyl)-cyclobutane

Send

Send

Metric Ton KG G Pound L ML

Send

Send