1,6-Dimethyl-4-isopropyl-8-methoxy-1,2,3,4-tetrahydronaphthalene

Base Information

• Chemical Name: 1,6-Dimethyl-4-isopropyl-8-methoxy-1,2,3,4-tetrahydronaphthalene
• CAS No.: 71306-08-6
• Molecular Formula: C₁₆H₂₄O
• Molecular Weight: 232.366
• Mol file: 71306-08-6.mol

Synonyms:1,2,3,4-Tetrahydro-5-methoxy-4,7-dimethyl-1-isopropylnaphthalene;1,6-Dimethyl-4-isopropyl-8-methoxy-1,2,3,4-tetrahydronaphthalene

Chemical Property of 1,6-Dimethyl-4-isopropyl-8-methoxy-1,2,3,4-tetrahydronaphthalene

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,6-Dimethyl-4-isopropyl-8-methoxy-1,2,3,4-tetrahydronaphthalene

There total 23 articles about 1,6-Dimethyl-4-isopropyl-8-methoxy-1,2,3,4-tetrahydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 0.28%

2-methoxy-4-methyl-1-(6-methylhept-5-en-2-yl)benzene (66879-51-4) → 8-Methoxycalamenene (71306-08-6)

Guidance literature:

With PPA; at 90 - 100 ℃; for 1.5h;

Reference yield:

4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol (122427-58-1) → 8-Methoxycalamenene (71306-08-6)

Guidance literature:

With PPA; at 90 - 100 ℃; for 1.5h;

Reference yield:

5-(2'-methoxy-4'-methylphenyl)hexanoic acid (122427-55-8) → 8-Methoxycalamenene (71306-08-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 2.2 g / concd. H₂SO₄ / 10 h / Heating

2: 1.) Mg / 1.) ether, 2.) ether, 6 h

3: 210 mg / iodine / benzene / 10 h / Heating

4: 0.220 g / polyphosphoric acid / 1.5 h / Heating

With PPA; sulfuric acid; iodine; magnesium; In benzene;

upstream raw materials:

2-methoxy-4-methyl-1-(6-methylhept-5-en-2-yl)benzene

2-(2-Methoxy-4-methyl-phenyl)-6-methyl-heptanol-⁽²⁾

4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol

glutaric anhydride,

Downstream raw materials:

cis-8-hydroxycalamenene

trans-8-hydroxycalamenene