4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol

Base Information

• Chemical Name: 4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol
• CAS No.: 122427-58-1
• Molecular Formula: C₁₆H₂₆O₂
• Molecular Weight: 250.381
• Mol file: 122427-58-1.mol

Synonyms:4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol

Chemical Property of 4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol

There total 18 articles about 4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methyl 5-(2'-methoxy-4'-methylphenyl)hexanoate (76337-12-7) + methyl iodide (74-88-4) → 4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol (122427-58-1)

Guidance literature:

methyl iodide; With magnesium; In diethyl ether; for 1h; Reflux;

methyl 5-(2'-methoxy-4'-methylphenyl)hexanoate; In diethyl ether; for 1h; Reflux;

With ammonium chloride; In diethyl ether;

DOI:10.1080/00397910903174382

Reference yield: 93.0%

ethyl 5-(4-methyl-2-methoxylphenyl)hexanoate (71841-61-7) + methyl iodide (74-88-4) → 4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol (122427-58-1)

Guidance literature:

methyl iodide; With magnesium; In diethyl ether; for 1h; Reflux;

ethyl 5-(4-methyl-2-methoxylphenyl)hexanoate; In diethyl ether; for 1h; Reflux;

DOI:10.1002/jccs.201000059

Reference yield:

2-(2-methoxy-4-methylphenyl)but-3-en-2-ol (1257259-78-1) → 4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol (122427-58-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: propionic acid / 170 °C / Microwave irradiation

2.1: palladium 10% on activated carbon; hydrogen / acetic acid; ethyl acetate / 24 h / 1140.08 Torr

3.1: magnesium / diethyl ether / 1 h / Reflux

3.2: 1 h / Reflux

With palladium 10% on activated carbon; hydrogen; magnesium; propionic acid; In diethyl ether; acetic acid; ethyl acetate;

DOI:10.1002/jccs.201000059

upstream raw materials:

methyl magnesium iodide

methyl 5-(2'-methoxy-4'-methylphenyl)hexanoate

methyl iodide

glutaric anhydride,

Downstream raw materials:

8-Methoxycalamenene

2-methoxy-4-methyl-1-(6-methylhept-5-en-2-yl)benzene