Chemical Property of Triacetin
Chemical Property:
- Appearance/Colour:colourless liquid with a bitter taste
- Vapor Pressure:0.0141mmHg at 25°C
- Melting Point:3 °C(lit.)
- Refractive Index:n25/D 1.429-1.431(lit.)
- Boiling Point:258 °C at 760 mmHg
- Flash Point:93.9 °C
- PSA：78.90000
- Density:1.16 g/mL at 25 °C(lit.)
- LogP:0.04430
- Storage Temp.:Sealed in dry,Room Temperature
- Solubility.:Soluble in water, miscible with ethanol (96 per cent) and toluene.
- Water Solubility.:64.0 g/L (20 ºC)
- XLogP3:0.2
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:8
- Exact Mass:218.07903816
- Heavy Atom Count:15
- Complexity:229
- Purity/Quality:
-
98% min *data from raw suppliers
Triacetin *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
23-24/25
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Chemical Classes:Other Classes -> Esters, Other
- Canonical SMILES:CC(=O)OCC(COC(=O)C)OC(=O)C
- Inhalation Risk:A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C.
- Effects of Short Term Exposure:The substance is mildly irritating to the skin.
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Uses
As a plasticizer and fragrance fixative, ink solvent, also used in medicine and dye synthesis.
As a chromatographic fixative, solvent, toughener and fragrance fixative.
Humectants; carrier solvents; plasticizers; it can absorb carbon dioxide from the natural gas.
In the production of cosmetics, pharmaceuticals and dyes, plasticizers for cigarette filter rods, and so on.
Applied in cosmetics, casting, medicine, dyes and other industries. This product is non-toxic, non-irritating.
As the substrate for the determination of lipase, perfume fixative, solvent, gas chromatographic fixative (maximum temperature of 85 ℃, solvent: methanol, chloroform), separation of gas and aldehyde analysis. Triacetin, a component of cigarette filters, induced a
contact dermatitis in a worker at a cigarette manufacturers. Triacetin is a colorless, oily liquid of slight fatty odor and bitter taste. It is soluble with water and is miscible with alcohol and ether. It functions in foods as a humectant and solvent. As fixative in perfumery; solvent in manufacture of celluloid, photographic films. Technical triacetin (a mixture of mono-, di-, and small quantities of triacetin) as a solvent for basic dyes, particularly indulines, and tannin in dyeing.
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Description
§ 184.1901(a) Triacetin (C8H14O6), also known as 1,2,3-propanetriol
triacetate or glyceryl triacetate, is the triester of glycerin and acetic
acid. Triacetin can be prepared by heating glycerin with acetic
anhydride alone or in the presence of finely divided potassium
hydrogen sulfate. It can also be prepared by the reaction of oxygen
with a liquid-phase mixture of allyl acetate and acetic acid using
a bromide salt as a catalyst.
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Therapeutic Function
Topical antifungal
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Clinical Use
Glyceryl triacetate (Enzactin, Fungacetin) is a colorless, oilyliquid with a slight odor and a bitter taste. The compound issoluble in water and miscible with alcohol and most organicsolvents.The activity of triacetin is a result of the acetic acid releasedby hydrolysis of the compound by esterases presentin the skin. Acid release is a self-limiting process becausethe esterases are inhibited below pH 4.
