4-(4-aMino-3-chlorophenoxy)-7-Methoxyquinoline-6-carboxaMide

Base Information

Chemical Name:4-(4-aMino-3-chlorophenoxy)-7-Methoxyquinoline-6-carboxaMide
CAS No.:417722-93-1
Molecular Formula:C17H14ClN3O3
Molecular Weight:343.769
Hs Code.:
Mol file:417722-93-1.mol

Synonyms:4-(4-aMino-3-chlorophenoxy)-7-Methoxyquinoline-6-carboxaMide;Lenvatinib Impurity c;4-(4-amino-3-chlorophenoxy)-7-methoxy-6-Quinolinecarboxamide;4-(3-chloro-4-ureidophenoxy)-7-methoxyquinoline-6-carboxylic acid;Lenvatinib impurity

Suppliers and Price of 4-(4-aMino-3-chlorophenoxy)-7-Methoxyquinoline-6-carboxaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Amino-3-chlorophenoxy)-7-methoxy-6-quinolinecarboxamide
250mg
$ 235.00

AK Scientific
4-(4-Amino-3-chlorophenoxy)-7-methoxyquinoline-6-carboxamide
1g
$ 1680.00

Total 26 raw suppliers

Chemical Property of 4-(4-aMino-3-chlorophenoxy)-7-Methoxyquinoline-6-carboxaMide

Chemical Property:

Boiling Point:577.2±50.0 °C(Predicted)
PKA:15.46±0.30(Predicted)
PSA：100.46000
Density:1.407±0.06 g/cm3(Predicted)
LogP:4.65170
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

4-(4-Amino-3-chlorophenoxy)-7-methoxy-6-quinolinecarboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4-(4-Amino-3-chlorophenoxy)-7-methoxy-6-quinolinecarboxamide is an impurity of Lenvatinib (L329400), CAS# 417716-92-8.4-(4-Amino-3-chlorophenoxy)-7-methoxy-6-quinolinecarboxamide is also used in pharmaceutical studies with an analytical role as a reference standard in an HPLC method for analyzing Lenvatinib or its salt, allowing a strong specificity, accuracy, precision, and high sensitivity.

Technology Process of 4-(4-aMino-3-chlorophenoxy)-7-Methoxyquinoline-6-carboxaMide

There total 17 articles about 4-(4-aMino-3-chlorophenoxy)-7-Methoxyquinoline-6-carboxaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

: 4-(3-chloro-4-nitrophenoxy)-7-methoxy-6-quinolinecarboxamide

: 417722-93-1
4?(4?amino?3?chlorophenoxy)?7?methoxyquinoline?6?carboxamide

Guidance literature:: With hydrogen; In methanol; at 20 ℃; under 7500.75 Torr; Reagent/catalyst; Pressure;

Reference yield: 98.8%

: 417721-36-9
4‐chloro‐7‐methoxyquinoline‐6‐carboxamide

: 17609-80-2
4-amino-3-chlorophenol

: 417722-93-1
4?(4?amino?3?chlorophenoxy)?7?methoxyquinoline?6?carboxamide

Guidance literature:: With potassium hydroxide; In dimethyl sulfoxide; at 65 - 70 ℃; for 2h; Temperature; Reagent/catalyst; Solvent; Concentration; Inert atmosphere; Large scale;