(S)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE

Base Information

• Chemical Name: (S)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE
• CAS No.: 1210934-04-5
• Molecular Formula: C₆H₁₃NO
• Molecular Weight: 115.175
• Hs Code.: 2933990090
• Mol file: 1210934-04-5.mol

Synonyms:(S)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE;(S)-(1-Methylpyrrolidin-3-yl)Methanol;(S)-1-Methyl-3-hydroxyMethyl-pyrrolidine;(3S)-1-Methyl-3-pyrrolidinemethanol;[(3S)-1-methylpyrrolidin-3-yl]methanol

Chemical Property of (S)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE

Chemical Property:

• Boiling Point: 141.7±13.0 °C(Predicted)
• PKA: 14.93±0.10(Predicted)
• PSA: 23.47000
• Density: 0.973±0.06 g/cm3(Predicted)
• LogP: -0.13170
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

(S)-(1-Methylpyrrolidin-3-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE

There total 12 articles about (S)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(R)-(+)-3-(hydroxymethyl)pyrrolidine (5082-74-6,85310-69-6,110013-18-8,110013-19-9) + methyl iodide (74-88-4) → (R)-1-methyl-3-hydroxymethylpyrrolidine (1210935-33-3,1210934-04-5)

Guidance literature:

With potassium carbonate; In acetonitrile; at 55 - 65 ℃; for 2h;

Reference yield: 60.0%

trimethylamine-N-oxide (1184-78-7) + allyl alcohol (107-18-6) → (1-methyl-3-pirrolidinyl)methanol (5021-33-0,1210934-04-5)

Guidance literature:

With DAL; In tetrahydrofuran; at -78 ℃;

Reference yield:

tert-butyl (R)-3-hydroxymethylpyrrolidine-1-carboxylate (138108-72-2) → (R)-1-methyl-3-hydroxymethylpyrrolidine (1210935-33-3,1210934-04-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 70 ℃; for 4h;

upstream raw materials:

1-(1-methyl-pyrrolidin-3-yl)-ethane-1,2-diol

trimethylamine-N-oxide

allyl alcohol

1-methyl-pyrrolidin-2-one

Downstream raw materials:

1-benzyl-1H-pyrazol-4-carboxylic acid [5-[3-((S)-1-methylpyrrolidin-2-ylmethoxy)phenyl]-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]amide

1-benzyl-1H-pyrazol-4-carboxylic acid {5-[3-((S)-1-methylpyrrolidin-2-ylmethoxy)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}amide

(S)-1-methyl-2-[3-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxymethyl]pyrrolidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1210934-04-5 (S)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE

Send

Send

Metric Ton KG G Pound L ML

Send

Send