(R)-alpha-Methylbenzenebutanol

Base Information

• Chemical Name: (R)-alpha-Methylbenzenebutanol
• CAS No.: 73494-49-2
• Molecular Formula: C11H16O
• Molecular Weight: 164.247
• Mol file: 73494-49-2.mol

Synonyms:(R)-alpha-methylbenzenebutanol

Chemical Property of (R)-alpha-Methylbenzenebutanol

Chemical Property:

• PSA: 20.23000
• LogP: 2.39010

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-alpha-Methylbenzenebutanol

There total 25 articles about (R)-alpha-Methylbenzenebutanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(S)-5-phenylpent-4-yn-2-ol (927385-39-5) → (S)-(+)-5-phenyl-2-pentanol (2344-71-0,65511-08-2,73494-49-2,87068-85-7)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; for 1.5h; Inert atmosphere;

DOI:10.1021/ol203413w

Reference yield: 80.0%

4S-Benzyloxy-1-phenyl-1-pentanone (87118-98-7) → (S)-(+)-5-phenyl-2-pentanol (2344-71-0,65511-08-2,73494-49-2,87068-85-7)

Guidance literature:

With hydrogenchloride; hydrogen; palladium-carbon; water; In toluene;

Reference yield: 78.0%

racemic 5-phenylpentan-2-ol + MANDELIC ACID (611-71-2,611-72-3,17199-29-0,90-64-2) → (2R)-5-Phenyl-2-pentanol (73494-49-2)

Guidance literature:

In toluene; benzene;

upstream raw materials:

(2S,3R)-5-Phenylpentane-2,3-diol

p-toluenesulfonyl chloride

5-phenylpent-1-ene

5-phenyl-2-pentanone

Downstream raw materials:

(S)-4-bromo-2-(5-phenyl-2-pentoxy)anisole

(R)-4-bromo-2-(5-phenyl-2-pentoxy)anisole

(S)-5-hydroxy-2-methyl-7-[(R)-5-phenyl-2-pentyloxy]-2,3-dihydroquinolin-4(1H)-one

(2S)-1-formyl-5-hydroxy-2-methyl-4-oxo-3-(3-oxobutyl)-7-[(R)-5-phenyl-2-pentyloxy]-2,3-dihydroquinoline