(R)-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethane-1,2-diol

Base Information

Chemical Name:(R)-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethane-1,2-diol
CAS No.:303176-45-6
Molecular Formula:C11H13FO3
Molecular Weight:212.221
Hs Code.:
European Community (EC) Number:608-459-4
DSSTox Substance ID:DTXSID20458726
Wikidata:Q76416796
Mol file:303176-45-6.mol

Synonyms:303176-45-6;(1'R,2R)-2-(1',2'-Dihydroxyethyl)-6-fluorochromane;(R)-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethane-1,2-diol;(1R)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethane-1,2-diol;SCHEMBL2257084;DTXSID20458726;(1R)-1-[(2R)-6-FLUORO-3,4-DIHYDRO-2H-1-BENZOPYRAN-2-YL]ETHANE-1,2-DIOL;(1 inverted exclamation mark R,2R)-2-(1 inverted exclamation mark ,2 inverted exclamation mark -Dihydroxyethyl)-6-fluorochromane

Suppliers and Price of (R)-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethane-1,2-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1’R,2R)-2-(1’,2’-Dihydroxyethyl)-6-fluorochromane
1 g
$ 1110.00

TRC
(1’R,2R)-2-(1’,2’-Dihydroxyethyl)-6-fluorochromane
100 mg
$ 140.00

Biosynth Carbosynth
(1'R,2R)-2-(1',2'-Dihydroxyethyl)-6-fluorochromane
1 g
$ 1528.80

Biosynth Carbosynth
(1'R,2R)-2-(1',2'-Dihydroxyethyl)-6-fluorochromane
50 mg
$ 140.00

Biosynth Carbosynth
(1'R,2R)-2-(1',2'-Dihydroxyethyl)-6-fluorochromane
500 mg
$ 840.00

Biosynth Carbosynth
(1'R,2R)-2-(1',2'-Dihydroxyethyl)-6-fluorochromane
250 mg
$ 462.50

Biosynth Carbosynth
(1'R,2R)-2-(1',2'-Dihydroxyethyl)-6-fluorochromane
100 mg
$ 255.00

Total 20 raw suppliers

Chemical Property of (R)-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethane-1,2-diol

Chemical Property:

Vapor Pressure:1.31E-06mmHg at 25°C
Melting Point:92-94 °C
Boiling Point:384.8°C at 760 mmHg
PKA:14.25±0.20(Predicted)
Flash Point:175.6°C
Density:1.308g/cm³
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly, Heated), Methanol (Slightly)
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:212.08487243
Heavy Atom Count:15
Complexity:212

Purity/Quality:

99.9% ^*data from raw suppliers

(1’R,2R)-2-(1’,2’-Dihydroxyethyl)-6-fluorochromane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=CC(=C2)F)OC1C(CO)O
Isomeric SMILES:C1CC2=C(C=CC(=C2)F)O[C@H]1[C@@H](CO)O
Uses (+)-Nebivolol intermediate.

Technology Process of (R)-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethane-1,2-diol

There total 29 articles about (R)-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%