(2,5-Difluorobenzyl)(4-methoxybenzyl)amine

Base Information

• Chemical Name: (2,5-Difluorobenzyl)(4-methoxybenzyl)amine
• CAS No.: 212393-25-4
• Molecular Formula: C₁₅H₁₅F₂NO
• Molecular Weight: 263.287
• DSSTox Substance ID: DTXSID00395529
• Wikidata: Q82195664
• Mol file: 212393-25-4.mol

Synonyms:212393-25-4;(2,5-DIFLUOROBENZYL)(4-METHOXYBENZYL)AMINE;CHEMBRDG-BB 5551609;N-[(2,5-difluorophenyl)methyl]-1-(4-methoxyphenyl)methanamine;DTXSID00395529;AKOS005867313;N-(2,5-Difluorobenzyl)-1-(4-methoxyphenyl)methanamine

Chemical Property of (2,5-Difluorobenzyl)(4-methoxybenzyl)amine

Chemical Property:

• Vapor Pressure: 6.6E-05mmHg at 25°C
• Boiling Point: 344.4°C at 760 mmHg
• Flash Point: 162.1°C
• Density: 1.174g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 263.11217043
• Heavy Atom Count: 19
• Complexity: 257

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CNCC2=C(C=CC(=C2)F)F

Technology Process of (2,5-Difluorobenzyl)(4-methoxybenzyl)amine

There total 2 articles about (2,5-Difluorobenzyl)(4-methoxybenzyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methoxybenzyl alcohol (105-13-5) → (2,5-Difluoro-benzyl)-(4-methoxy-benzyl)-amine (212393-25-4)

Guidance literature:

Multi-step reaction with 2 steps

1: polymer supported perruthenate / toluene / 2 h / 80 °C

2: polymer supported cyanoborohydride / methanol; toluene / 72 h / Ambient temperature

With polymer supported cyanoborohydride; polymer supported perruthenate; In methanol; toluene;

Reference yield:

2,5-difluorobenzylamine (85118-06-5) + 4-methoxy-benzaldehyde (123-11-5) → (2,5-Difluoro-benzyl)-(4-methoxy-benzyl)-amine (212393-25-4)

Guidance literature:

With polymer supported cyanoborohydride; In methanol; toluene; for 72h; Yield given; Ambient temperature;

upstream raw materials:

2,5-difluorobenzylamine

4-methoxy-benzaldehyde

4-Methoxybenzyl alcohol