Ethylamine, 1,2-diphenyl-, hydrochloride

Base Information

• Chemical Name: Ethylamine, 1,2-diphenyl-, hydrochloride
• CAS No.: 24301-89-1
• Molecular Formula: C₁₄H₁₅N*ClH
• Molecular Weight: 233.741
• Mol file: 24301-89-1.mol

Synonyms:Ethylamine, 1,2-diphenyl-, hydrochloride

Chemical Property of Ethylamine, 1,2-diphenyl-, hydrochloride

Chemical Property:

• Vapor Pressure: 0.000575mmHg at 25°C
• Boiling Point: 311.1°C at 760 mmHg
• Flash Point: 136.8°C
• PSA: 26.02000
• LogP: 4.43140

Purity/Quality:

99% ^*data from raw suppliers

ETHYLAMINE, 1,2-DIPHENYL-, HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethylamine, 1,2-diphenyl-, hydrochloride

There total 17 articles about Ethylamine, 1,2-diphenyl-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

deoxybenzoin oxime (952-06-7) → 1,2-diphenyl-1-ethylamine hydrochloride (60000-09-1,24301-89-1)

Guidance literature:

With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In ethanol; water; under 760.051 Torr;

Reference yield:

1-tert-butyl-N-(1,2-diphenylvinyl)-1,1-dimethylsilanamine → 1,2-diphenyl-1-ethylamine hydrochloride (60000-09-1,24301-89-1)

Guidance literature:

1-tert-butyl-N-(1,2-diphenylvinyl)-1,1-dimethylsilanamine; With 2.5% wt Pd/C; hydrogen; In benzene-d6; at 20 ℃; for 40h; under 760.051 Torr;

With hydrogenchloride; In diethyl ether; benzene-d6; ethyl acetate;

DOI:10.1021/jacs.7b13783

Reference yield:

phenyl benzyl ketone (451-40-1) → 1,2-diphenyl-1-ethylamine hydrochloride (60000-09-1,24301-89-1)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol / 6 h / 60 °C

2: hydrogenchloride; hydrogen / palladium 10% on activated carbon / ethanol; water / 760.05 Torr

With hydrogenchloride; hydroxylamine hydrochloride; hydrogen; sodium acetate; palladium 10% on activated carbon; In ethanol; water;

upstream raw materials:

deoxybenzoin oxime

phenyl benzyl ketone

benzhydrylidene-benzyl-amine

benzyl bromide

Downstream raw materials:

3-Hydroxy-1,2-diphenyl-1-propanone

N-(1,2-diphenylethyl)benzamide

Refernces

• 1、 -. "N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF". Paragraph 0375. . Retrieved 2013/03/26.
• 2、 Roe, Caroline,Hobbs, Heather,Stockman, Robert A.. "One-pot synthesis of chiral nonracemic amines". experimental part. p. 9452 - 9459. Retrieved 2012/01/06.