METHYL (3S)-3-AMINO-3-(4-HYDROXYPHENYL)PROPANOATE

Base Information

Chemical Name:METHYL (3S)-3-AMINO-3-(4-HYDROXYPHENYL)PROPANOATE
CAS No.:177966-65-3
Molecular Formula:C10H13NO3
Molecular Weight:195.218
Hs Code.:

Synonyms:METHYL (3S)-3-AMINO-3-(4-HYDROXYPHENYL)PROPANOATE;METHYL 3-AMINO-3-(4-HYDROXYPHENYL)PROPANOATE

Suppliers and Price of METHYL (3S)-3-AMINO-3-(4-HYDROXYPHENYL)PROPANOATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Methyl 3-amino-3-(4-hydroxyphenyl)propanoate 97%
1g
$ 950.00

JR MediChem
Benzenepropanoicacid,?-amino-4-hydroxy-,methylester,(?S)- 96%
1g
$ 680.00

Crysdot
(S)-Methyl3-amino-3-(4-hydroxyphenyl)propanoate 95+%
1g
$ 432.00

Total 7 raw suppliers

Chemical Property of METHYL (3S)-3-AMINO-3-(4-HYDROXYPHENYL)PROPANOATE

Chemical Property:

PSA：72.55000
LogP:1.65540

Purity/Quality:

97% ^*data from raw suppliers

Methyl 3-amino-3-(4-hydroxyphenyl)propanoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of METHYL (3S)-3-AMINO-3-(4-HYDROXYPHENYL)PROPANOATE

There total 5 articles about METHYL (3S)-3-AMINO-3-(4-HYDROXYPHENYL)PROPANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 134430-95-8
methyl (3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-3-(4-benzyloxyphenyl)propanoate

: 177966-65-3
methyl (3S)-3-amino-3-(4-hydroxyphenyl)propanoate

Guidance literature:: With hydrogen; acetic acid; palladium dihydroxide; In methanol; water; at 20 ℃; for 18h; under 760 Torr;
DOI:10.1016/S0957-4166(00)82354-X

Reference yield:

: methyl (αR)-3-(N-benzyl-N-α-methylbenzylamino)-3-(4-benzyloxyphenyl)propanoate

: 177966-65-3
methyl (3S)-3-amino-3-(4-hydroxyphenyl)propanoate

: 177966-66-4
(R)-β-tyrosine methyl ester

Guidance literature:: With hydrogen; acetic acid; palladium dihydroxide; In methanol; water; at 20 ℃; under 760 Torr; Title compound not separated from byproducts;
DOI:10.1016/j.tetasy.2006.05.008

Reference yield:

: 84184-51-0
(E)-methyl 3-(4-(benzyloxy)phenyl)acrylate

: 177966-65-3
methyl (3S)-3-amino-3-(4-hydroxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) BuLi / 1.) hexane, THF, 0 deg C, 15 min, 2.) -78 deg C, 15 min

2: 100 percent / H₂, acetic acid / 20percent Pd(OH)2/C / methanol; H₂O / 18 h / 20 °C / 760 Torr

With n-butyllithium; hydrogen; acetic acid; palladium dihydroxide; In methanol; water;
DOI:10.1016/S0957-4166(00)82354-X