3'-FLUORO-4-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID

Base Information

Chemical Name:3'-FLUORO-4-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID
CAS No.:22494-43-5
Molecular Formula:C13H9FO3
Molecular Weight:232.21
Hs Code.:2922299090
Mol file:22494-43-5.mol

Synonyms:AKOS BAR-0029;3'-FLUORO-4-HYDROXY[1,1'-BIPHENYL]-3-CARBOXYLIC ACID;3'-FLUORO-4-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID;5-(3-Fluorophenyl)-2-hydroxybenzoic acid, 5-(3-Fluorophenyl)salicyclic acid

Suppliers and Price of 3'-FLUORO-4-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3'-Fluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
1 g
$ 736.00

Crysdot
3'-Fluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylicacid 95+%
1g
$ 623.00

Apolloscientific
3'-Fluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylicacid
1g
$ 667.00

American Custom Chemicals Corporation
3'-FLUORO-4-HYDROXY-[1,1'-BIPHENYL]-3-CARBOXYLIC ACID 95.00%
1G
$ 855.86

American Custom Chemicals Corporation
3'-FLUORO-4-HYDROXY-[1,1'-BIPHENYL]-3-CARBOXYLIC ACID 95.00%
500MG
$ 739.20

Alichem
3'-Fluoro-4-hydroxybiphenyl-3-carboxylicacid
250mg
$ 470.40

Total 4 raw suppliers

Chemical Property of 3'-FLUORO-4-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID

Chemical Property:

PSA：57.53000
LogP:2.89650

Purity/Quality:

99% ^*data from raw suppliers

3'-Fluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3'-FLUORO-4-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID

There total 3 articles about 3'-FLUORO-4-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 89-55-4
5-bromosalicyclic acid

: 768-35-4
3-fluorophenylboronic acid

: 22494-43-5
3'-fluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid

Guidance literature:: With PdCl₂(NH₂CH₂COOH)₂; potassium carbonate; In water; at 20 ℃; for 24h;
DOI:10.1021/acs.jmedchem.0c01762

Reference yield:

: 372-19-0
meta-fluoroaniline

: 124-38-9,18923-20-1
carbon dioxide

: 100-66-3
methoxybenzene

: 22494-43-5
3'-fluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid

Guidance literature:: Multistep reaction; (i) isopentyl nitrite, (ii) aq. HI, AcOH, (iii) /BRN= 1900390/, K₂CO₃, (heating);
DOI:10.1021/jm00209a001