6-BROMO-2-METHOXYNAPHTHALENE-1-CARBALDEHYDE

Base Information

• Chemical Name: 6-BROMO-2-METHOXYNAPHTHALENE-1-CARBALDEHYDE
• CAS No.: 247174-18-1
• Molecular Formula: C12H9BrO2
• Molecular Weight: 265.106
• Hs Code.: 2913000090
• Mol file: 247174-18-1.mol

Synonyms:6-BROMO-2-METHOXYNAPHTHALENE-1-CARBALDEHYDE;6-BroMo-2-Methoxy-1-naphthaldehyde

Chemical Property of 6-BROMO-2-METHOXYNAPHTHALENE-1-CARBALDEHYDE

Chemical Property:

• Melting Point: 110 °C
• Boiling Point: 234-240 °C(Press: 15 Torr)
• PSA: 26.30000
• Density: 1.511±0.06 g/cm3(Predicted)
• LogP: 3.42340
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

6-Bromo-2-methoxy-1-naphthaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-BROMO-2-METHOXYNAPHTHALENE-1-CARBALDEHYDE

There total 6 articles about 6-BROMO-2-METHOXYNAPHTHALENE-1-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Dichloromethyl methyl ether (4885-02-3) + 2-Bromo-6-methoxynaphthalene (5111-65-9) → 6-bromo-2-methoxynaphthalene-1-carbaldehyde (247174-18-1)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at 40 ℃; for 2h;

DOI:10.1016/j.bmcl.2007.10.079

Reference yield: 100.0%

6-Bromo-2-hydroxy-1-naphthaldehyde (53815-56-8) + methyl iodide (74-88-4) → 6-bromo-2-methoxynaphthalene-1-carbaldehyde (247174-18-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 3h; Inert atmosphere;

Reference yield: 88.0%

2-Bromo-6-methoxynaphthalene (5111-65-9) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 6-bromo-2-methoxynaphthalene-1-carbaldehyde (247174-18-1)

Guidance literature:

2-Bromo-6-methoxynaphthalene; N,N-dimethyl-formamide; With trichlorophosphate; In toluene; at 100 ℃; for 5h;

With water; sodium acetate; In toluene;

DOI:10.1016/j.ejmech.2011.02.050

upstream raw materials:

2-Bromo-6-methoxynaphthalene

N-methyl-N-phenylformamide

N,N-dimethyl-formamide

Dichloromethyl methyl ether

Downstream raw materials:

6-(4-fluorophenyl)-2-methoxy-1-naphthaldehyde

2-methoxy-6-(3-methoxyphenyl)-1-naphthaldehyde

(6-bromo-2-methoxynaphth-1-yl)-(2-acetamido-4,6-dimethoxyphenyl)ketone

(6-bromo-2-methoxynaphth-1-yl)[2-(6-bromo-2-methoxy-1-naphthoylamino)-4,6-dimethoxyphenyl]ketone