1,6-ANHYDRO-2,O-BENZOYL-3,4-O-ISOPROPYLIDENE-BETA-D-GALACTOPYRANOSE

Base Information

• Chemical Name: 1,6-ANHYDRO-2,O-BENZOYL-3,4-O-ISOPROPYLIDENE-BETA-D-GALACTOPYRANOSE
• CAS No.: 67307-84-0
• Molecular Formula: C16H18O6
• Molecular Weight: 306.315
• Mol file: 67307-84-0.mol

Synonyms:1,6-ANHYDRO-2,O-BENZOYL-3,4-O-ISOPROPYLIDENE-BETA-D-GALACTOPYRANOSE;1,6-ANHYDRO-2,O-BENZOYL-3,4-O-ISOPROPYLIDENE-SS-D-GALACTOPYRANOSE

Chemical Property of 1,6-ANHYDRO-2,O-BENZOYL-3,4-O-ISOPROPYLIDENE-BETA-D-GALACTOPYRANOSE

Chemical Property:

• Boiling Point: 413.7±45.0 °C(Predicted)
• PSA: 63.22000
• Density: 1.33±0.1 g/cm3(Predicted)
• LogP: 1.48720

Purity/Quality:

97% ^*data from raw suppliers

1,6-ANHYDRO-2,O-BENZOYL-3,4-O-ISOPROPYLIDENE-BETA-D-GALACTOPYRANOSE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,6-ANHYDRO-2,O-BENZOYL-3,4-O-ISOPROPYLIDENE-BETA-D-GALACTOPYRANOSE

There total 2 articles about 1,6-ANHYDRO-2,O-BENZOYL-3,4-O-ISOPROPYLIDENE-BETA-D-GALACTOPYRANOSE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

benzoyl chloride (98-88-4) + 1,6-anhydro-3,4-O-isopropylidene-β-D-galactopyranose (52579-97-2) → 1,6-Anhydro-2-O-benzoyl-3,4-O-isopropyliden-β-D-galactopyranose (67307-84-0)

Guidance literature:

In pyridine; 1.) 0 deg C, 1 h, 2.) 2 h;

Reference yield:

2,2-dimethoxy-propane (77-76-9) → 1,6-Anhydro-2-O-benzoyl-3,4-O-isopropyliden-β-D-galactopyranose (67307-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / p-TsOH / acetone / 16 h / Ambient temperature

2: 89 percent / pyridine / 3 h / Ambient temperature

With pyridine; toluene-4-sulfonic acid; In acetone;

DOI:10.1021/jo00111a012

Reference yield: 93.0%

1,6-Anhydro-2-O-benzoyl-3,4-O-isopropyliden-β-D-galactopyranose (67307-84-0) → 1,6-Anhydro-2-O-benzoyl-β-D-galactopyranose (67337-01-3)

Guidance literature:

With acetic acid; In water; for 1h; Heating;

upstream raw materials:

benzoyl chloride

1,6-anhydro-3,4-O-isopropylidene-β-D-galactopyranose

2,2-dimethoxy-propane

Downstream raw materials:

1,6-Anhydro-2-O-benzoyl-β-D-galactopyranose

(1'R,2R,4S)-2-(2-O-Benzoyl-1-hydroxyethyl)-4-(hydroxymethyl)-1,3-dioxolane

(1'R,2R,4R)-4-<<(tert-Butyldiphenylsilyl)oxy>methyl>-2-(2-O-benzoyl-1-hydroxyethyl)-1,3-dioxolane

1,6-Anhydro-2-O-benzoyl-4-deoxy-4-β-D-glucopyranose