1,6-Anhydro-3,4-O-isopropylidene-beta-D-galactopyranose

Base Information

• Chemical Name: 1,6-Anhydro-3,4-O-isopropylidene-beta-D-galactopyranose
• CAS No.: 52579-97-2
• Molecular Formula: C9H14O5
• Molecular Weight: 202.207
• Hs Code.: 2932990090
• Nikkaji Number: J591.509K
• Mol file: 52579-97-2.mol

Synonyms:52579-97-2;1,6-Anhydro-3,4-O-isopropylidene-beta-D-galactopyranose;1,6-Anhydro-3,4-o-isopropylidene-b-D-galactopyranose;SCHEMBL7644312;MFCD00269908;W-202982

Chemical Property of 1,6-Anhydro-3,4-O-isopropylidene-beta-D-galactopyranose

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 145-146°C
• Refractive Index: 1.495
• Boiling Point: 340.6 °C at 760 mmHg
• Flash Point: 159.8 °C
• PSA: 57.15000
• Density: 1.289g/cm³
• LogP: -0.37750
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform, Dichloromethane
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 202.08412354
• Heavy Atom Count: 14
• Complexity: 254

Purity/Quality:

98% ^*data from raw suppliers

1,6-Anhydro-3,4-O-isopropylidene-b-D-galactopyranose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(OC2C3COC(O3)C(C2O1)O)C
• Isomeric SMILES: CC1(O[C@H]2[C@H]3CO[C@H](O3)[C@@H]([C@H]2O1)O)C

Technology Process of 1,6-Anhydro-3,4-O-isopropylidene-beta-D-galactopyranose

There total 9 articles about 1,6-Anhydro-3,4-O-isopropylidene-beta-D-galactopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,6-anhydro-β-D-galactopyranose (644-76-8) + 2,2-dimethoxy-propane (77-76-9) → 1,6-anhydro-3,4-O-isopropylidene-β-D-galactopyranose (52579-97-2)

Guidance literature:

With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; for 1h; Ambient temperature;

Reference yield: 92.0%

1,6-anhydro-D-galactopyranose (498-07-7,644-76-8,10339-41-0,10339-42-1,13051-71-3,14059-68-8,14059-73-5,14168-65-1,14274-90-9,22224-56-2,22658-88-4,42744-19-4,60619-47-8,67999-95-5,107795-40-4,129097-81-0) + acetone (67-64-1) → 1,6-anhydro-3,4-isopropylidene-D-galactopyranose (17073-95-9,41092-26-6,41092-28-8,52579-97-2)

Guidance literature:

With 4 A molecular sieve; toluene-4-sulfonic acid; for 2h; Heating;

DOI:10.1080/00397919208021665

Reference yield:

D-Galactose (59-23-4) → 1,6-anhydro-3,4-O-isopropylidene-β-D-galactopyranose (52579-97-2) + 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose (4064-06-6)

Guidance literature:

With sulfuric acid; acetone; Erhitzen des Reaktionsprodukts unter vermindertem Druck;

DOI:10.1039/jr9390000387

upstream raw materials:

D-Galactose

1,6-anhydro-β-D-galactopyranose

acetone

2,2-dimethoxy-propane

Downstream raw materials:

1,6-Anhydro-2-O-benzoyl-3,4-O-isopropyliden-β-D-galactopyranose

O³,O⁴-isopropylidene-O²-(toluene-4-sulfonyl)-1,6-anhydro-β-D-galactopyranose

O²-benzyl-O³,O⁴-isopropyliden-1,6-anhydro-β-D-galactopyranose

1,6-anhydro-β-D-galactopyranose