1-ETHYL-4-T-BUTYL-2-DIETHYLPHOSPHONOSUCCINATE

Base Information

Chemical Name:1-ETHYL-4-T-BUTYL-2-DIETHYLPHOSPHONOSUCCINATE
CAS No.:77924-28-8
Molecular Formula:C14H27O7P
Molecular Weight:338.338
Hs Code.:2931900090
Mol file:77924-28-8.mol

Synonyms:1-ETHYL-4-T-BUTYL-2-DIETHYLPHOSPHONOSUCCINATE;1-Ethyl-4-tert-butyl-2-diethylphosphonosuccinate;Butanedioic acid 2-(diethoxyphosphoryl)-1-ethyl-4-tertbutyl ester

Suppliers and Price of 1-ETHYL-4-T-BUTYL-2-DIETHYLPHOSPHONOSUCCINATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Ethyl4-(tert-Butyl)2-(diethylphosphono)succinate
2.5g
$ 1190.00

TRC
1-Ethyl4-(tert-Butyl)2-(diethylphosphono)succinate
250mg
$ 150.00

Total 9 raw suppliers

Chemical Property of 1-ETHYL-4-T-BUTYL-2-DIETHYLPHOSPHONOSUCCINATE

Chemical Property:

Boiling Point:143 °C(Press: 0.13 Torr)
PSA：97.94000
Density:1.113±0.06 g/cm3(Predicted)
LogP:2.91600
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

98%, ^*data from raw suppliers

1-Ethyl4-(tert-Butyl)2-(diethylphosphono)succinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-Ethyl 4-(tert-Butyl) 2-(diethyl phosphono)succinate, is used in the synthesis of Dalesconols A and B, which are the potent immunosuppressant agents.

Technology Process of 1-ETHYL-4-T-BUTYL-2-DIETHYLPHOSPHONOSUCCINATE

There total 1 articles about 1-ETHYL-4-T-BUTYL-2-DIETHYLPHOSPHONOSUCCINATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 5292-43-3
bromoacetic acid tert-butyl ester

: 77924-28-8
4-tert-butyl 1-ethyl 2-(diethoxyphosphoryl)succinate

Guidance literature:: diethoxyphosphoryl-acetic acid ethyl ester; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; Inert atmosphere;

bromoacetic acid tert-butyl ester; In tetrahydrofuran; mineral oil; at 0 - 25 ℃; Inert atmosphere;
DOI:10.1002/anie.201002264

Reference yield: 100.0%

: 2646-91-5
2,3-difluorobenzaldehyde

: 77924-28-8
4-tert-butyl 1-ethyl 2-(diethoxyphosphoryl)succinate

: C₁₇H₂₀F₂O₄

Guidance literature:: 4-tert-butyl 1-ethyl 2-(diethoxyphosphoryl)succinate; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 1h;

2,3-difluorobenzaldehyde; In tetrahydrofuran; mineral oil; at 20 ℃; for 3h;

Reference yield: 99.0%

: 7507-86-0
2-bromo-5-methoxy-benzaldehyde

: 77924-28-8
4-tert-butyl 1-ethyl 2-(diethoxyphosphoryl)succinate

: 4-(t-butyl) 1-ethyl 2-(2-bromo-5-methoxystyryl)succinate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; In acetonitrile; at 25 ℃; for 12h; Inert atmosphere;
DOI:10.1002/anie.201002264