1-Benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:1-Benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine
CAS No.:281192-93-6
Molecular Formula:C14H11BrN2
Molecular Weight:287.159
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40572938
Nikkaji Number:J1.284.257K
Wikidata:Q82461470
Mol file:281192-93-6.mol

Synonyms:281192-93-6;1-benzyl-3-bromo-7-azaindole;1-Benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine;1-Benzyl-3-bromo-pyrrolo[2,3-b]pyridine;1-benzyl-3-bromopyrrolo[2,3-b]pyridine;SCHEMBL14857618;DTXSID40572938;XGECCZZIAJKFBI-UHFFFAOYSA-N;AKOS015949409;AB91434;CS-W001521;AS-59539;A1-33152;J-504279;1-BENZYL-3-BROMO-PYRROLO[2,3-B]PYRIDINE[281192-93-6]

Suppliers and Price of 1-Benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Benzyl-3-bromo-pyrrolo[2,3-b]pyridine >95%
250mg
$ 530.00

Matrix Scientific
1-Benzyl-3-bromo-pyrrolo[2,3-b]pyridine >95%
500mg
$ 750.00

Matrix Scientific
1-Benzyl-3-bromo-pyrrolo[2,3-b]pyridine >95%
1g
$ 1143.00

Crysdot
1-Benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine 97%
1g
$ 803.00

American Custom Chemicals Corporation
1-BENZYL-3-BROMO-1H-PYRROLO[2,3-B]PYRIDINE 95.00%
500MG
$ 1402.17

American Custom Chemicals Corporation
1-BENZYL-3-BROMO-1H-PYRROLO[2,3-B]PYRIDINE 95.00%
250MG
$ 1159.62

American Custom Chemicals Corporation
1-BENZYL-3-BROMO-1H-PYRROLO[2,3-B]PYRIDINE 95.00%
1G
$ 1834.14

Alichem
1-Benzyl-3-bromo-7-azaindole
1g
$ 1718.70

Alichem
1-Benzyl-3-bromo-7-azaindole
250mg
$ 727.60

Alichem
1-Benzyl-3-bromo-7-azaindole
500mg
$ 970.20

Total 11 raw suppliers

Chemical Property of 1-Benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

PSA：17.82000
LogP:3.84710
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:286.01056
Heavy Atom Count:17
Complexity:253

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-Benzyl-3-bromo-pyrrolo[2,3-b]pyridine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C=C(C3=C2N=CC=C3)Br

Technology Process of 1-Benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine

There total 5 articles about 1-Benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 152955-68-5
1-benzyl-1H-pyrrolo[2,3-b]-pyridine

: 281192-93-6
1-benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: With romine; In dichloromethane; at 0 - 20 ℃;
DOI:10.3987/COM-99-8792

Reference yield:

: 74420-15-8
3-bromo-1H-pyrrolo[2,3-b]pyridine

: 100-39-0
benzyl bromide

: 281192-93-6
1-benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 3-bromo-1H-pyrrolo[2,3-b]pyridine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; for 0.833333h;

benzyl bromide; In N,N-dimethyl-formamide; mineral oil; for 48h;

Reference yield:

: 271-63-6
7-Azaindole

: 281192-93-6
1-benzyl-3-bromo-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-acetamide / 0.5 h

1.2: 96 percent / N,N-dimethyl-acetamide / 20 °C

2.1: 95 percent / romine / CH₂Cl₂ / 0 - 20 °C

With romine; sodium hydride; In dichloromethane; N,N-dimethyl acetamide; 1.1: Metallation / 1.2: Alkylation / 2.1: Bromination;
DOI:10.3987/COM-99-8792