6-Bromo-8-chloro-2H-benzo[B][1,4]oxazin-3(4H)-one

Base Information

Chemical Name:6-Bromo-8-chloro-2H-benzo[B][1,4]oxazin-3(4H)-one
CAS No.:121564-96-3
Molecular Formula:C₈H₅BrClNO₂
Molecular Weight:262.49
Hs Code.:
DSSTox Substance ID:DTXSID20558472
Wikidata:Q82440794
Mol file:121564-96-3.mol

Synonyms:121564-96-3;6-BROMO-8-CHLORO-2H-BENZO[B][1,4]OXAZIN-3(4H)-ONE;6-Bromo-8-chloro-2H-1,4-benzoxazin-3(4H)-one;6-bromo-8-chloro-4H-1,4-benzoxazin-3-one;2H-1,4-BENZOXAZIN-3(4H)-ONE, 6-BROMO-8-CHLORO-;MFCD09835007;6-BROMO-8-CHLORO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-3-ONE;SCHEMBL4290482;DTXSID20558472;HARMFWNFNHJNIM-UHFFFAOYSA-N;WEA56496;AC2135;AKOS017553703;AB53064;CS-W020716;CS-12593;SY100549;EN300-215479;A921754;Z1269122069

Suppliers and Price of 6-Bromo-8-chloro-2H-benzo[B][1,4]oxazin-3(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Bromo-8-chloro-3,4-dihydro-2H-1,4-benzoxazin-3-one
100mg
$ 310.00

TRC
6-Bromo-8-chloro-3,4-dihydro-2H-1,4-benzoxazin-3-one
50mg
$ 200.00

American Custom Chemicals Corporation
6-BROMO-8-CHLORO-2H-BENZO[B][1,4]OXAZIN-3-(4H)-ONE 95.00%
5MG
$ 495.45

Alichem
6-Bromo-8-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one
25g
$ 6834.00

Alichem
6-Bromo-8-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one
10g
$ 4180.80

Alichem
6-Bromo-8-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one
5g
$ 2653.20

AK Scientific
6-Bromo-8-chloro-2H-benzo[B][1,4]oxazin-3(4H)-one
25g
$ 768.00

AK Scientific
6-Bromo-8-chloro-2H-benzo[B][1,4]oxazin-3(4H)-one
5g
$ 313.00

Total 4 raw suppliers

Chemical Property of 6-Bromo-8-chloro-2H-benzo[B][1,4]oxazin-3(4H)-one

Chemical Property:

PSA：41.82000
LogP:2.51850
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:260.91922
Heavy Atom Count:13
Complexity:226

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-8-chloro-3,4-dihydro-2H-1,4-benzoxazin-3-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(=O)NC2=C(O1)C(=CC(=C2)Br)Cl

Technology Process of 6-Bromo-8-chloro-2H-benzo[B][1,4]oxazin-3(4H)-one

There total 3 articles about 6-Bromo-8-chloro-2H-benzo[B][1,4]oxazin-3(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 943994-32-9
methyl 2-(4-bromo-2-chloro-6-nitrophenoxy)acetate

: 121564-96-3
6-bromo-8-chloro-2H-1,4-benzoxazin-3(4H)-one

Guidance literature:: With acetic acid; zinc; at 100 ℃; for 0.75h;

Reference yield:

: 79-07-2
Chloroacetamide

: 121564-96-3
6-bromo-8-chloro-2H-1,4-benzoxazin-3(4H)-one

Guidance literature:: With potassium carbonate; In ethanol;

Reference yield:

: 58349-01-2
4-bromo-6-chloro-2-nitrophenol

: 121564-96-3
6-bromo-8-chloro-2H-1,4-benzoxazin-3(4H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 65 °C

2: acetic acid; zinc / 12 h / 100 °C

With potassium carbonate; acetic acid; zinc; In N,N-dimethyl-formamide;
DOI:10.1021/jm2011645