Technology Process of 1,3-Benzodioxole-4-acetic acid, α,7-dihydroxy-6-(methoxymethoxy)-, ethyl ester
There total 3 articles about 1,3-Benzodioxole-4-acetic acid, α,7-dihydroxy-6-(methoxymethoxy)-, ethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3 A molecular sieve; lithium chloride;
In
toluene;
at 20 ℃;
for 24h;
DOI:10.1021/ja0571794
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 96 percent / NaH / diethyl ether; dimethylformamide / 0 - 20 °C
2.1: n-BuLi; B(OMe)3 / tetrahydrofuran
2.2: 95 percent / AcOH; H2O2 / 0 - 20 °C
3.1: 97 percent / LiCl; 3 Angstroem molecular sieves / toluene; various solvent(s) / 24 h / 20 °C
With
n-butyllithium; Trimethyl borate; 3 A molecular sieve; sodium hydride; lithium chloride;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; toluene;
3.1: Friedel-Crafts reaction;
DOI:10.1021/ja0571794
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-BuLi; B(OMe)3 / tetrahydrofuran
1.2: 95 percent / AcOH; H2O2 / 0 - 20 °C
2.1: 97 percent / LiCl; 3 Angstroem molecular sieves / toluene; various solvent(s) / 24 h / 20 °C
With
n-butyllithium; Trimethyl borate; 3 A molecular sieve; lithium chloride;
In
tetrahydrofuran; toluene;
2.1: Friedel-Crafts reaction;
DOI:10.1021/ja0571794
