Chemical Property of diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate
Chemical Property:
- Melting Point:139-141 °C(Solv: cyclohexane (110-82-7); benzene (71-43-2))
- Boiling Point:525.5±50.0 °C(Predicted)
- PKA:2.05±0.70(Predicted)
- PSA:55.84000
- Density:1.183±0.06 g/cm3(Predicted)
- LogP:4.11790
- Storage Temp.:Sealed in dry,Room Temperature
- Solubility.:Soluble in DMSO (up to 5 mg/ml).
- Purity/Quality:
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97% *data from raw suppliers
Diethyl1-Benzyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Description
BML-278 (120533-76-8) is a structurally novel activator of SIRT1 (EC50=1 μM). Displays selectivity over SIRT2 and 3 (EC50=25 and 50 μM respectively). Cell permeable.
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Uses
Diethyl 1-Benzyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate is a cell-permeable and potent SIRT activator that induces cell cycle arrest. SIRT modulators have therapeutic potential the treatment of cancer, cardiovascular, metabolic, inflammatory, and neurodegenerative diseases.