1-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-N-methylmethanamine

Base Information

• Chemical Name: 1-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-N-methylmethanamine
• CAS No.: 943106-34-1
• Molecular Formula: C₈H₁₅N₃
• Molecular Weight: 153.227
• Hs Code.: 2933199090
• European Community (EC) Number: 823-943-7
• DSSTox Substance ID: DTXSID60428327
• Mol file: 943106-34-1.mol

Synonyms:943106-34-1;1-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-N-methylmethanamine;N-[(1-ethyl-5-methyl-1H-pyrazol-4-yl)methyl]-N-methylamine;1-(1-ethyl-5-methylpyrazol-4-yl)-N-methylmethanamine;MFCD02253773;[(1-ethyl-5-methyl-1H-pyrazol-4-yl)methyl](methyl)amine;SCHEMBL1719143;(1-Ethyl-5-methyl-1H-pyrazol-4-ylmethyl)-methyl-amine;1-(1-ethyl-5-methyl-pyrazol-4-yl)-N-methyl-methanamine;DTXSID60428327;STK263679;AKOS000266035;FS-1905;CS-0240315;EN300-227756;(1-Ethyl-5-methyl-1H-pyrazol-4-ylmethyl)methylamine;(1-ethyl-5-methyl-1 h-pyrazol-4-ylmethyl)-methyl-amine

Chemical Property of 1-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-N-methylmethanamine

Chemical Property:

• PSA: 29.85000
• LogP: 1.32170
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 153.126597491
• Heavy Atom Count: 11
• Complexity: 116

Purity/Quality:

98%Min ^*data from raw suppliers

N-[(1-Ethyl-5-methyl-1H-pyrazol-4-yl)methyl]-N-methylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1C(=C(C=N1)CNC)C

Technology Process of 1-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-N-methylmethanamine

There total 3 articles about 1-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-N-methylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

N-ethyl-1H-5-methylpyrazole-4-carboxaldehyde (933778-29-1) + methylamine (74-89-5) → C8H15N3 (943106-34-1)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; at 27 ℃; for 96h;

Reference yield:

1-ethyl-1H-pyrazole (2817-71-2) → C8H15N3 (943106-34-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran / 2 h / -50 - -20 °C / Inert atmosphere

1.2: -20 - 20 °C

2.1: trichlorophosphate / 2 h / 90 - 100 °C

3.1: sodium tetrahydroborate / tetrahydrofuran / 96 h / 27 °C

With sodium tetrahydroborate; n-butyllithium; trichlorophosphate; In tetrahydrofuran;

Reference yield:

1-ethyl-5-methyl-1H-pyrazole (43155-07-3) → C8H15N3 (943106-34-1)

Guidance literature:

Multi-step reaction with 2 steps

1: trichlorophosphate / 2 h / 90 - 100 °C

2: sodium tetrahydroborate / tetrahydrofuran / 96 h / 27 °C

With sodium tetrahydroborate; trichlorophosphate; In tetrahydrofuran;

upstream raw materials:

1-ethyl-1H-pyrazole

1-ethyl-5-methyl-1H-pyrazole

N-ethyl-1H-5-methylpyrazole-4-carboxaldehyde

methylamine