4-CHLORO-3-FLUOROBENZOIC ACID ETHYL ESTER

Base Information

• Chemical Name: 4-CHLORO-3-FLUOROBENZOIC ACID ETHYL ESTER
• CAS No.: 203573-08-4
• Molecular Formula: C₉H₈ClFO₂
• Molecular Weight: 202.613
• Hs Code.: 2916399090
• Mol file: 203573-08-4.mol

Synonyms:4-CHLORO-3-FLUOROBENZOIC ACID ETHYL ESTER;Ethyl 4-chloro-3-fluoroethyl benzoate

Chemical Property of 4-CHLORO-3-FLUOROBENZOIC ACID ETHYL ESTER

Chemical Property:

• PSA: 26.30000
• LogP: 2.65580
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-3-fluorobenzoicacidethylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLORO-3-FLUOROBENZOIC ACID ETHYL ESTER

There total 3 articles about 4-CHLORO-3-FLUOROBENZOIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl ether (60-29-7,927820-24-4) + 2,4-dichloro-5-fluorobenzoyl chloride (86393-34-2) → ethyl 4-chloro-3-fluorobenzoate (203573-08-4) + 2,4-Dichloro-5-fluorobenzoic acid ethyl ester (103318-75-8)

Guidance literature:

In ethanol;

Reference yield:

copper (12775-96-1,15158-11-9,15721-63-8,16941-75-6,17493-86-6,19498-52-3,20499-83-6,20499-84-7,20499-85-8,20499-86-9,20573-10-8,20573-11-9,21595-51-7,21595-52-8,22206-52-6,26445-28-3,28959-95-7,37362-93-9,39417-05-5,54603-16-6,54603-23-5,54603-32-6,54603-40-6,54603-48-4,54603-81-5,54603-89-3,56316-56-4,95985-91-4,122297-32-9,7440-50-8) + 2,4-Dichloro-5-fluorobenzoic acid ethyl ester (103318-75-8) → ethyl 4-chloro-3-fluorobenzoate (203573-08-4)

Guidance literature:

With propionic acid; In toluene;

Reference yield:

ethanol (64-17-5) + 4-chloro-3-fluorobenzoic acid (403-17-8) → ethyl 4-chloro-3-fluorobenzoate (203573-08-4)

Guidance literature:

With sulfuric acid; Reflux;

DOI:10.1039/c8ra00161h DOI:10.3906/kim-1901-45

upstream raw materials:

copper

2,4-Dichloro-5-fluorobenzoic acid ethyl ester

diethyl ether

2,4-dichloro-5-fluorobenzoyl chloride

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