10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene

Base Information

• Chemical Name: 10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene
• CAS No.: 416857-85-7
• Molecular Formula: C₂₉H₂₂O₂
• Molecular Weight: 402.492
• Mol file: 416857-85-7.mol

Synonyms:10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene

Chemical Property of 10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene

There total 4 articles about 10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl magnesium iodide (917-64-6) + 2,2-diphenyl-2H-pyrano[6,5-b]fluorenone (416857-78-8) → 10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene (416857-85-7)

Guidance literature:

In diethyl ether;

DOI:10.1016/S0040-4020(01)01187-5

Reference yield:

1-hydroxy-9H-fluoren-9-one (6344-60-1) → 10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene (416857-85-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 31 percent / PPTS / CHCl₃ / 72 h / Heating

2: 85 percent / diethyl ether

With pyridinium p-toluenesulfonate; In diethyl ether; chloroform;

DOI:10.1016/S0040-4020(01)01187-5

Reference yield:

1-methoxy-9-fluorenone (42523-15-9) → 10-hydroxy-10-methyl-2,2-diphenyl-2H-pyrano[6,5-b]fluorene (416857-85-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / aq. HBr 47 percent / acetic acid / 8 h / Heating

2: 31 percent / PPTS / CHCl₃ / 72 h / Heating

3: 85 percent / diethyl ether

With hydrogen bromide; pyridinium p-toluenesulfonate; In diethyl ether; chloroform; acetic acid;

DOI:10.1016/S0040-4020(01)01187-5

upstream raw materials:

methyl magnesium iodide

2,2-diphenyl-2H-pyrano[6,5-b]fluorenone

1-hydroxy-9H-fluoren-9-one

1-methoxy-9-fluorenone

Downstream raw materials:

4-methoxylbiphenyl

2-(4-methoxyphenyl)naphthalene

2-methoxy-6-(4-methoxyphenyl)naphthalene

4’-methoxy-N,N-diphenyl-[1,1’-biphenyl]-4-amine