D-Tryptophan, N-L-phenylalanyl-

Base Information

Chemical Name:D-Tryptophan, N-L-phenylalanyl-
CAS No.:66421-20-3
Molecular Formula:C20H21N3O3
Molecular Weight:351.399
Hs Code.:
DSSTox Substance ID:DTXSID40216643
Nikkaji Number:J61.744J
Wikidata:Q83092901

Synonyms:D-Tryptophan, N-L-phenylalanyl-;66421-20-3;Tryptophan, N-(3-phenyl-L-alanyl)-, D-;BRN 5145119;(R)-2-((S)-2-Amino-3-phenylpropanamido)-3-(1H-indol-3-yl)propanoic acid;SCHEMBL11873471;DTXSID40216643;LS-158161;(R)-2-((S)-2-Amino-3-phenylpropanamido)-3-(1H-indol-3-yl)propanoicacid;(2R)-2-[(2S)-2-AMINO-3-PHENYLPROPANAMIDO]-3-(1H-INDOL-3-YL)PROPANOIC ACID

Suppliers and Price of D-Tryptophan, N-L-phenylalanyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of D-Tryptophan, N-L-phenylalanyl-

Chemical Property:

Vapor Pressure:6.85E-20mmHg at 25°C
Boiling Point:688.3°Cat760mmHg
Flash Point:370.1°C
PSA：108.21000
Density:1.319g/cm³
LogP:2.94100
XLogP3:-0.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:351.15829154
Heavy Atom Count:26
Complexity:493

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)O)N
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)N[C@H](CC2=CNC3=CC=CC=C32)C(=O)O)N

Technology Process of D-Tryptophan, N-L-phenylalanyl-

There total 3 articles about D-Tryptophan, N-L-phenylalanyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35661-40-6
N-Fmoc L-Phe

: 163619-04-3
1-tert-butoxycarbonyl-N-[(9-fluorenyl)methoxycarbonyl]-D-tryptophan

: 66421-20-3
L-Phe-D-Trp-OH

Guidance literature:: 1-tert-butoxycarbonyl-N-[(9-fluorenyl)methoxycarbonyl]-D-tryptophan; With 1-methyl-1H-imidazole; diisopropyl-carbodiimide; at 0 - 20 ℃; for 2h; Green chemistry;

With piperidine; In N,N-dimethyl-formamide; for 0.133333h; Green chemistry;

N-Fmoc L-Phe; Further stages; Green chemistry;
DOI:10.1016/j.tetlet.2019.151058

Reference yield:

: 35661-40-6
N-Fmoc L-Phe

: 143824-78-6,163619-04-3
3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester

: 66421-20-3
L-Phe-D-Trp-OH

: 24587-41-5
phenylalanyltryptophane

Guidance literature:: 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester; With 1-methyl-1H-imidazole; diisopropyl-carbodiimide; at 0 - 20 ℃; for 2h; Green chemistry;

With piperidine; In N,N-dimethyl-formamide; for 0.133333h; Green chemistry;

N-Fmoc L-Phe; Further stages; Green chemistry;
DOI:10.1016/j.tetlet.2019.151058

Reference yield:

: 2577-90-4
methyl (2S)-2-amino-3-phenylpropanoate

: 153-94-6,27732-43-0,80206-30-0,27813-82-7
D-tryptophan

: 66421-20-3
L-Phe-D-Trp-OH

: 2862-51-3
(3S,6S)-3,6-dibenzylpiperazine-2,5-dione

Guidance literature:: With aminolysin-A; In water; dimethyl sulfoxide; at 50 ℃; for 6h; pH=8; aq. phosphate buffer; Enzymatic reaction;
DOI:10.1039/c0ob00403k