acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester

Base Information

• Chemical Name: acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester
• CAS No.: 452307-54-9
• Molecular Formula: C₂₁H₂₃BrO₅
• Molecular Weight: 435.315
• Mol file: 452307-54-9.mol

Synonyms:acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester

Chemical Property of acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester

There total 5 articles about acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dimethylmethoxybenzene (874-63-5) → acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester (452307-54-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: HCl / 1,1,2,2-tetrachloro-ethane / 1 h / 17 °C

1.2: 61 percent / AlCl₃ / 1,1,2,2-tetrachloro-ethane / 3 h / 55 °C

2.1: 92 percent / NaOH / ethanol / 20 °C

3.1: Br₂ / CH₂Cl₂ / 20 °C

4.1: AcOH

With hydrogenchloride; sodium hydroxide; bromine; acetic acid; In ethanol; dichloromethane; 1,1,2,2-tetrachloroethane;

DOI:10.1021/jm020536q

Reference yield:

4-methoxy-2,6-dimethylbenzylaldehyde (19447-00-8) → acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester (452307-54-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / NaOH / ethanol / 20 °C

2: Br₂ / CH₂Cl₂ / 20 °C

3: AcOH

With sodium hydroxide; bromine; acetic acid; In ethanol; dichloromethane;

DOI:10.1021/jm020536q

Reference yield:

1-(4-methoxyphenyl)ethanone (100-06-1) → acetic acid, 2-bromo-1-(4-methoxy-2,6-dimethylphenyl)-3-(4-methoxyphenyl)-3-oxopropyl ester (452307-54-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / NaOH / ethanol / 20 °C

2: Br₂ / CH₂Cl₂ / 20 °C

3: AcOH

With sodium hydroxide; bromine; acetic acid; In ethanol; dichloromethane;

DOI:10.1021/jm020536q

upstream raw materials:

potassium acetate

2,3-dibromo-3-(4-methoxy-2,6-dimethylphenyl)-1-(4-methoxyphenyl)propan-1-one

3,5-dimethylmethoxybenzene

4-methoxy-2,6-dimethylbenzylaldehyde

Downstream raw materials:

3-(4-methoxy-2,6-dimethylphenyl)-1-(4-methoxyphenyl)propynone

1-[7-methoxy-10-(4-methoxyphenyl)-5-methylphenanthren-2-yl]ethanone

4'-methoxy-2',6'-dimethyl-2-(4-methoxybenzoyl)biphenyl-4-carbonitrile

7-methoxy-10-(4-methoxyphenyl)-5-methylphenanthren-2-carbonitrile