2-Thia-6-azaspiro[3.3]heptane oxalic acid salt (2:1)

Base Information

Chemical Name:2-Thia-6-azaspiro[3.3]heptane oxalic acid salt (2:1)
CAS No.:920491-09-4
Molecular Formula:C₅H₉NS
Molecular Weight:115.199
Hs Code.:2934999090
Mol file:920491-09-4.mol

Synonyms:2-thia-6-azaspiro[3.3]heptane

Suppliers and Price of 2-Thia-6-azaspiro[3.3]heptane oxalic acid salt (2:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Synthonix
2-Thia-6-azaspiro[3.3]heptane 95+%
10g
$ 3860.00

SynQuest Laboratories
2-Thia-6-azaspiro[3.3]heptane
250 mg
$ 592.00

SynQuest Laboratories
2-Thia-6-azaspiro[3.3]heptane
1 g
$ 1708.00

SynQuest Laboratories
2-Thia-6-azaspiro[3.3]heptane
500 mg
$ 1148.00

Matrix Scientific
2-Thia-6-azaspiro[3.3]heptane 95+%
1g
$ 3036.00

AK Scientific
2-Thia-6-azaspiro[3.3]heptane
1g
$ 802.00

Total 10 raw suppliers

Chemical Property of 2-Thia-6-azaspiro[3.3]heptane oxalic acid salt (2:1)

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-Thia-6-azaspiro[3.3]heptane 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-Thia-6-azaspiro[3.3]heptane is a useful moiety in anticancer medication as because it makes the molecule a better EGFR kinase inhibitor.

Technology Process of 2-Thia-6-azaspiro[3.3]heptane oxalic acid salt (2:1)

There total 5 articles about 2-Thia-6-azaspiro[3.3]heptane oxalic acid salt (2:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1233142-91-0
6-tosyl-2-thia-6-azaspiro[3.3]heptane

: 920491-09-4
2-thia-6-azaspiro[3.3]heptane

Guidance literature:: With magnesium; In methanol; at 20 ℃; for 3h; Sonication;

Reference yield:

: 1522-92-5
2,2-bis(bromomethyl)-3-bromo-propan-1-ol

: 920491-09-4
2-thia-6-azaspiro[3.3]heptane

Guidance literature:: Multi-step reaction with 5 steps

1: potassium hydroxide / ethanol / 48 h / 25 - 100 °C

2: hydrogen bromide; acetic acid / diethyl ether / 0.5 h / 20 °C

3: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C

4: sodiumsulfide nonahydrate / water; acetonitrile / 4 h / 50 °C

5: magnesium / methanol / 3 h / 20 °C / Sonication

With sodiumsulfide nonahydrate; carbon tetrabromide; hydrogen bromide; magnesium; acetic acid; triphenylphosphine; potassium hydroxide; In methanol; diethyl ether; ethanol; dichloromethane; water; acetonitrile;

Reference yield:

: 13573-28-9
6-(p-toluenesulfonyl)-2-oxa-6-azaspiro[3.3]heptane

: 920491-09-4
2-thia-6-azaspiro[3.3]heptane

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen bromide; acetic acid / diethyl ether / 0.5 h / 20 °C

2: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C

3: sodiumsulfide nonahydrate / water; acetonitrile / 4 h / 50 °C

4: magnesium / methanol / 3 h / 20 °C / Sonication

With sodiumsulfide nonahydrate; carbon tetrabromide; hydrogen bromide; magnesium; acetic acid; triphenylphosphine; In methanol; diethyl ether; dichloromethane; water; acetonitrile;