Phenol, 2,4-dichloro-6-methoxy-

Base Information

• Chemical Name: Phenol, 2,4-dichloro-6-methoxy-
• CAS No.: 16766-31-7
• Molecular Formula: C7H6 Cl2 O2
• Molecular Weight: 193.029
• DSSTox Substance ID: DTXSID30168344
• Nikkaji Number: J593.431A
• Wikidata: Q83037929
• Mol file: 16766-31-7.mol

Synonyms:4,6-dichloroguaiacol;16766-31-7;2,4-DICHLORO-6-METHOXYPHENOL;Phenol, 2,4-dichloro-6-methoxy-;4,6-Dichloro-guaiacol;4,6-Dichloro-2-methoxyphenol;SCHEMBL9332746;DTXSID30168344;2,4-Dichloro-6-methoxyphenol #;AKOS040756979;HY-133608;CS-0128389

Chemical Property of Phenol, 2,4-dichloro-6-methoxy-

Chemical Property:

• Vapor Pressure: 0.00994mmHg at 25°C
• Boiling Point: 255.8°Cat760mmHg
• Flash Point: 108.5°C
• PSA: 29.46000
• Density: 1.421g/cm³
• LogP: 2.70760
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 191.9744848
• Heavy Atom Count: 11
• Complexity: 132

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=C(C(=CC(=C1)Cl)Cl)O

Technology Process of Phenol, 2,4-dichloro-6-methoxy-

There total 8 articles about Phenol, 2,4-dichloro-6-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

4-Chloroguaiacol (16766-30-6) → 4,6-Dichloroguaiacol (16766-31-7)

Guidance literature:

With sodium hydroxide; sodium hypochlorite; In water; at 25 ℃; for 0.666667h;

DOI:10.1016/S0045-6535(00)00568-3

Reference yield:

methanol (67-56-1) + 2,4-dichloro-6-diazocyclohexa-2,4-dien-1-one (63969-35-7) → 4,6-Dichloroguaiacol (16766-31-7) + 2,4-dichlorophenol (120-83-2,40477-79-0)

Guidance literature:

Yield given. Yields of byproduct given; Irradiation;

Reference yield:

4-chloro-6,6-dimethoxycyclohexa-2,4-dienone (1120310-43-1) → 4,5-dichloroguaiacol (2460-49-3) + 4,6-Dichloroguaiacol (16766-31-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; water; at 20 ℃; for 0.0333333h; Overall yield = 90 %;

DOI:10.1016/j.tetlet.2015.11.012

upstream raw materials:

3,5-dichloro-2-nitroanisole

(2,4-dichloro-6-methoxy-phenoxy)-acetic acid

methanol

2,4-dichloro-6-diazocyclohexa-2,4-dien-1-one

Downstream raw materials:

(2,4-dichloro-6-methoxy-phenoxy)-acetic acid

[2-(2,4-Dichloro-6-methoxy-phenoxy)-ethyl]-dimethyl-amine

[2-(2,4-Dichloro-6-methoxy-phenoxy)-ethyl]-diethyl-amine