2,4,4'-Trimethoxychalcone

Base Information

Chemical Name:2,4,4'-Trimethoxychalcone
CAS No.:18493-34-0
Molecular Formula:C18H18O4
Molecular Weight:298.339
Hs Code.:2914500090
European Community (EC) Number:242-378-1
Nikkaji Number:J222.220E
ChEMBL ID:CHEMBL418246
Mol file:18493-34-0.mol

Synonyms:2,4,4'-Trimethoxychalcone;18493-34-0;(E)-3-(2,4-dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one;(2E)-3-(2,4-dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one;3-(2,4-dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one;24533-49-1;CHEMBL418246;SCHEMBL3215700;4'-Methoxy-2,4-dimethoxychalcone;BDBM50107259;MFCD00016649;STK888806;AKOS000991686;VU0488878-1;AB00107696-01;SR-01000234448;SR-01000234448-1;Z46053785;F1006-0084;3-(2,4-Dimethoxy-phenyl)-1-(4-methoxy-phenyl)-propenone;(E)-3-(2,4-Dimethoxy-phenyl)-1-(4-methoxy-phenyl)-propenone

Suppliers and Price of 2,4,4'-Trimethoxychalcone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2,4,4'-TRIMETHOXYCHALCONE Aldrich
50mg
$ 57.00

Biosynth Carbosynth
2,4,4'-Trimethoxychalcone
5 g
$ 50.00

Biosynth Carbosynth
2,4,4'-Trimethoxychalcone
50 g
$ 250.00

Biosynth Carbosynth
2,4,4'-Trimethoxychalcone
25 g
$ 162.50

Biosynth Carbosynth
2,4,4'-Trimethoxychalcone
10 g
$ 75.00

AK Scientific
2,4,4'-Trimethoxychalcone
25g
$ 269.00

AK Scientific
2,4,4'-Trimethoxychalcone
10g
$ 151.00

Total 7 raw suppliers

Chemical Property of 2,4,4'-Trimethoxychalcone

Chemical Property:

Boiling Point:478.3°Cat760mmHg
Flash Point:212°C
PSA：44.76000
Density:1.139g/cm³
LogP:3.60850
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:298.12050905
Heavy Atom Count:22
Complexity:371

Purity/Quality:

99% ^*data from raw suppliers

2,4,4'-TRIMETHOXYCHALCONE Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)C=CC2=C(C=C(C=C2)OC)OC
Isomeric SMILES:COC1=CC=C(C=C1)C(=O)/C=C/C2=C(C=C(C=C2)OC)OC

Technology Process of 2,4,4'-Trimethoxychalcone

There total 3 articles about 2,4,4'-Trimethoxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 123-11-5
4-methoxy-benzaldehyde

: 829-20-9
2',4'-dimethoxyacetophenone

: 18493-34-0
3-(2,4-dimethoxyphenyl)-1-(4-methoxy-phenyl)propenone

Guidance literature:: With pyrrolidine anchored in non-ordered mesoporous silica hybrid materials; In toluene; at 200 ℃; for 10h; Sealed tube; Microwave irradiation;
DOI:10.1002/cctc.202101031

Reference yield: 86.0%

: 613-45-6
2,4-Dimethoxybenzaldehyde

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 18493-34-0
3-(2,4-dimethoxyphenyl)-1-(4-methoxy-phenyl)propenone

Guidance literature:: With sodium hydroxide; In ethanol; at 0 - 20 ℃;
DOI:10.1016/j.bmc.2009.11.066

Reference yield:

: 55991-65-6
[1-(4-methoxyphenyl)vinyloxy]trimethylsilane

: 613-45-6
2,4-Dimethoxybenzaldehyde

: 18493-34-0
3-(2,4-dimethoxyphenyl)-1-(4-methoxy-phenyl)propenone

Guidance literature:: With 4-tolylthallium(III) bis(trifluoroacetate); titanium tetrachloride; Yield given. Multistep reaction; 1.) benzene, RT, 30 min, 2.) THF, -78 deg C, 1.5 h, RT, 1 h;
DOI:10.1021/jo00240a016