3-phenyl propiolic acid (2-methyl)allyl ester

Base Information

• Chemical Name: 3-phenyl propiolic acid (2-methyl)allyl ester
• CAS No.: 868556-87-0
• Molecular Formula: C₁₃H₁₂O₂
• Molecular Weight: 200.237
• Mol file: 868556-87-0.mol

Synonyms:3-phenyl propiolic acid (2-methyl)allyl ester

Chemical Property of 3-phenyl propiolic acid (2-methyl)allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-phenyl propiolic acid (2-methyl)allyl ester

There total 2 articles about 3-phenyl propiolic acid (2-methyl)allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenylpropyolic acid (637-44-5) + 3-hydroxy-2-methyl-1-propene (513-42-8) → 3-phenyl propiolic acid (2-methyl)allyl ester (868556-87-0)

Guidance literature:

With dmap; diisopropyl-carbodiimide; In dichloromethane; at 25 ℃; for 4h; Inert atmosphere;

Reference yield: 83.0%

carbon dioxide (124-38-9,18923-20-1) + phenylacetylene (536-74-3) + 3-Chloro-2-methylpropene (563-47-3) → 3-phenyl propiolic acid (2-methyl)allyl ester (868556-87-0)

Guidance literature:

With caesium carbonate; silver(I) iodide; In N,N-dimethyl-formamide; at 60 ℃; for 24h; under 11251.1 Torr; Autoclave;

DOI:10.1016/j.tet.2012.08.053

Reference yield: 92.0%

3-phenyl propiolic acid (2-methyl)allyl ester (868556-87-0) + sodium ethanesulfinate (20035-08-9) → (E)-3-benzylidene-4-((ethylsulfonyl)methyl)-4-methyldihydrofuran-2(3H)-one

Guidance literature:

With dipotassium peroxodisulfate; nitric acid; silver nitrate; In acetonitrile; at 80 - 90 ℃; for 12h; Schlenk technique;

DOI:10.1021/acs.joc.6b02416

upstream raw materials:

phenylpropyolic acid

3-hydroxy-2-methyl-1-propene

carbon dioxide

phenylacetylene

Downstream raw materials:

(4-methylpent-4-en-1-yn-1-yl)benzene

1-benzoyl-5-methyl-3-oxabicyclo[3.1.0]hexan-2-one

5-methyl-7-phenyl-3-oxa-bicyclo[3.2.0]hept-6-en-2-one