bis(2,6-dimethylphenyl)glyoxal

Base Information

• Chemical Name: bis(2,6-dimethylphenyl)glyoxal
• CAS No.: 1225-22-5
• Molecular Formula: C₁₈H₁₈O₂
• Molecular Weight: 266.34
• Mol file: 1225-22-5.mol

Synonyms:bis(2,6-dimethylphenyl)glyoxal

Chemical Property of bis(2,6-dimethylphenyl)glyoxal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(2,6-dimethylphenyl)glyoxal

There total 14 articles about bis(2,6-dimethylphenyl)glyoxal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

oxalyl dichloride (79-37-8) + (2,6-dimethylphenyl)magnesium bromide (21450-64-6) → bis(2,6-dimethylphenyl)glyoxal (1225-22-5)

Guidance literature:

With copper(I) bromide; lithium bromide; In tetrahydrofuran; at 0 ℃; for 0.25h;

DOI:10.1016/0040-4039(95)01471-S

Reference yield: 70.0%

1,1'-oxalyldiimidazole (18637-83-7) + (2,6-dimethylphenyl)magnesium bromide (21450-64-6) → bis(2,6-dimethylphenyl)glyoxal (1225-22-5)

Guidance literature:

In tetrahydrofuran; at -30 ℃; for 15h;

DOI:10.1016/S0040-4039(00)79200-8

Reference yield:

2,6-dimethylbenzoic acid (632-46-2) → bis(2,6-dimethylphenyl)glyoxal (1225-22-5)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

2: methyl magnesium iodide; diethyl ether

With methyl magnesium iodide; thionyl chloride; diethyl ether;

upstream raw materials:

2,6-dimethylbenzoyl chloride

2,6-dimethyliodobenzene

carbon monoxide

1,1'-oxalyldiimidazole

Downstream raw materials:

2,6,2',6'-Tetramethyl-benzoin

α.α'-diacetoxy-2.6.2'.6'-tetramethyl-cis-stilbene

1,2-diacetoxy-1,2-bis(2,6-dimethylphenyl)ethene

2,6,2',6'-tetramethyl-3,3'-dinitro-benzil