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Saccharin sodium

Base Information Edit
  • Chemical Name:Saccharin sodium
  • CAS No.:128-44-9
  • Deprecated CAS:38279-26-4,1792234-08-2
  • Molecular Formula:C7H4NNaO3S
  • Molecular Weight:205.169
  • Hs Code.:2925110000
  • European Community (EC) Number:204-886-1,612-173-5
  • UNII:I4807BK602
  • DSSTox Substance ID:DTXSID5021253
  • Wikidata:Q27094367
  • NCI Thesaurus Code:C77139
  • RXCUI:1362914
  • ChEMBL ID:CHEMBL2219743
  • Mol file:128-44-9.mol
Saccharin sodium

Synonyms:Sodium saccharin;1,2-Benzisothiazol-3(2H)-one,1,1-dioxide, sodium salt (1:1);Saccharine Sodium USP;1,2-Benzisothiazol-3(2H)-one,1,1-dioxide, sodium salt (9CI);1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodiumderiv. (7CI);1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodium salt (8CI);Saccharin, sodium deriv. (6CI);1,2-Benzothiazol-3(2H)-one 1,1-dioxide sodiumsalt;Cristallose;Crystallose;Kristallose;Saxin;Sodium o-benzosulfimide;Sodiumo-sulfobenzimide;Sucram C 150;Sweeta;Sykose;Willosetten;o-Benzoylsulfimide sodium salt;

Chemical Property of Saccharin sodium Edit
Chemical Property:
  • Appearance/Colour:white crystalline powder 
  • Vapor Pressure:1.77E-08mmHg at 25°C 
  • Melting Point:>300 °C 
  • Boiling Point:438.9 °C at 760 mmHg 
  • PKA:0.003-0.003[at 20 ℃] 
  • Flash Point:219.3 °C 
  • PSA:77.94000 
  • Density:1.69[at 20℃] 
  • LogP:1.08240 
  • Storage Temp.:0-6°C 
  • Solubility.:H2O: 1 M at 20 °C, clear, colorless 
  • Water Solubility.:>=10 g/100 mL at 20 ºC 
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:0
  • Exact Mass:204.98095845
  • Heavy Atom Count:13
  • Complexity:308

99.00% *data from raw suppliers

Saccharin sodium salt hydrate ≥98.0% (titration) *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
  • Safety Statements: 24/25 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

  • Chemical Classes:Other Uses -> Food Additives
  • Canonical SMILES:C1=CC=C2C(=C1)C(=O)[N-]S2(=O)=O.[Na+]
  • Recent ClinicalTrials:Effect of Stevioside in Postpandrial Glucose in Healthy Adults
  • Description Saccharin sodium is a type of artificial or nonnutritive sweetener. It is 200 to 700 times sweeter than sucrose but has a bitter aftertaste. Saccharin and its salts do not occur naturally. Saccharin sodium is used in the production of various foods and pharmaceutical products including soft drinks, candy, biscuits, jams, chewing gum, tinned fruit, medicine and toothpaste.
  • Uses Sodium saccharin is the salt most frequently used in formulating soluble forms of this sweetening agent. It can be used in toothpaste, mouthwash, diet soft drinks, syrups, baked goods, ice cream, and other sweet foods and drinks. While it is certainly most famously used in food products, sodium saccharin is also used in the chemical and agricultural industries as an aid in the production of herbicides and pesticides. It is also used as part of a solution used to coat metals, such as gold and nickel. Major application of Sodium saccharine is the food industry as an additive in different products. It is used as a low calorie sweetener and stabilizer in a variety of food and drinks. In bakeries it is used to sweeten baked goods, breads, cookies and muffins. Due to its rapidly dissolving nature in water, it is used as an artificial sweetener in carbonated beverages and sodas. Saccharin Sodium is a flavoring agent and non-nutritive sweetener. It is a salt of saccharin widely used as sweetener in food and beverage. As a high-intensity sweetener, Saccharin Sodium can be used in a wide variety of industries including: food production, beverage, cosmetics, agriculture/animal feed, and various other industries. Saccharin Sodium Salt Hydrate can be used for the purification of recombinant polypeptides, such as antibodies.
Marketing and Price of Saccharin sodium
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Sigma-Aldrich
  • Saccharin sodium salt hydrate ≥98.0% (titration)
  • 500 g
  • $ 82.3
  • Sigma-Aldrich
  • Saccharin Sodium
  • 500mg
  • $ 70.4
  • Sigma-Aldrich
  • Saccharin sodium salt hydrate BioXtra, ≥99%
  • 250 g
  • $ 57.3
  • Sigma-Aldrich
  • Saccharin sodium European Pharmacopoeia (EP) Reference Standard
  • $ 190
  • Sigma-Aldrich
  • Saccharin sodium European Pharmacopoeia (EP) Reference Standard
  • s0050000
  • $ 190
  • Sigma-Aldrich
  • Saccharin sodium salt hydrate BioXtra, ≥99%
  • 1 kg
  • $ 176
  • Sigma-Aldrich
  • Saccharin sodium salt hydrate ≥98.0% (titration)
  • 1 kg
  • $ 158
  • Matrix Scientific
  • Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide 95+%
  • 5g
  • $ 45
  • Matrix Scientific
  • Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide 95+%
  • 100g
  • $ 288
  • Matrix Scientific
  • Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide 95+%
  • 25g
  • $ 122
Total 289 raw suppliers
Technology Process of Saccharin sodium

There total 4 articles about Saccharin sodium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium methylate; In methanol; at 20 - 22 ℃; for 6h;
Guidance literature:
Guidance literature:
Refernces Edit
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