[5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester

Base Information

Chemical Name:[5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester
CAS No.:1287760-82-0
Molecular Formula:C₁₈H₁₈N₄O₄S
Molecular Weight:386.431
Hs Code.:

Synonyms:[5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester

Suppliers and Price of [5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester

There total 5 articles about [5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 64-17-5
ethanol

: 586333-65-5
5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazole-3-carboxylic acid

: 1287760-82-0
[5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester

Guidance literature:: With diphenylphosphoranyl azide; triethylamine; In 1,4-dioxane; for 12h; Inert atmosphere; Reflux;
DOI:10.1021/jm2001376

Reference yield:

: 98-86-2
acetophenone

: 1287760-82-0
[5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C

2.1: ethanol / 1 h / 20 °C / Inert atmosphere

2.2: 2 h / Reflux; Inert atmosphere

3.1: water; lithium hydroxide / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

4.1: diphenylphosphoranyl azide; triethylamine / 1,4-dioxane / 12 h / Inert atmosphere; Reflux

With diphenylphosphoranyl azide; water; potassium hexamethylsilazane; triethylamine; lithium hydroxide; In tetrahydrofuran; 1,4-dioxane; ethanol; 4.1: Curtius rearrangement;
DOI:10.1021/jm2001376

Reference yield:

: potassium salt of ethyl 2-hydroxy-4-oxo-4-phenyl-2-butenoate

: 1287760-82-0
[5-phenyl-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethanol / 1 h / 20 °C / Inert atmosphere

1.2: 2 h / Reflux; Inert atmosphere

2.1: water; lithium hydroxide / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

3.1: diphenylphosphoranyl azide; triethylamine / 1,4-dioxane / 12 h / Inert atmosphere; Reflux

With diphenylphosphoranyl azide; water; triethylamine; lithium hydroxide; In tetrahydrofuran; 1,4-dioxane; ethanol; 3.1: Curtius rearrangement;
DOI:10.1021/jm2001376