2-(2-Naphthyl)-5-phenyl-1,3,4-oxadiazole

Base Information

• Chemical Name: 2-(2-Naphthyl)-5-phenyl-1,3,4-oxadiazole
• CAS No.: 967-72-6
• Molecular Formula: C18H12N2O
• Molecular Weight: 272.306
• European Community (EC) Number: 213-525-7
• NSC Number: 90802
• DSSTox Substance ID: DTXSID90242396
• Nikkaji Number: J298.570E
• Wikidata: Q83126079
• Mol file: 967-72-6.mol

Synonyms:2-(2-Naphthyl)-5-phenyl-1,3,4-oxadiazole;967-72-6;EINECS 213-525-7;2-phenyl-5-(2-naphthyl)-1,3,4-oxadiazol;NSC90802;DTXSID90242396;NSC 90802;NSC-90802

Chemical Property of 2-(2-Naphthyl)-5-phenyl-1,3,4-oxadiazole

Chemical Property:

• Vapor Pressure: 1.18E-08mmHg at 25°C
• Boiling Point: 472.8°Cat760mmHg
• Flash Point: 241.3°C
• Density: 1.219g/cm³
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 272.094963011
• Heavy Atom Count: 21
• Complexity: 342

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NN=C(O2)C3=CC4=CC=CC=C4C=C3

Technology Process of 2-(2-Naphthyl)-5-phenyl-1,3,4-oxadiazole

There total 6 articles about 2-(2-Naphthyl)-5-phenyl-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

benzoic acid hydrazide (613-94-5) + β-naphthaldehyde (66-99-9) → 2-naphthalen-2-yl-5-phenyl-[1,3,4]oxadiazole (967-72-6)

Guidance literature:

benzoic acid hydrazide; β-naphthaldehyde; In N,N-dimethyl-formamide; at 60 ℃; Inert atmosphere;

With N-ethyl-N,N-diisopropylamine; eosin y; In N,N-dimethyl-formamide; at 20 ℃; for 15h; Irradiation; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.02.022

Reference yield: 82.0%

2-naphthohydrazide (39627-84-4) + benzaldehyde (100-52-7) → 2-naphthalen-2-yl-5-phenyl-[1,3,4]oxadiazole (967-72-6)

Guidance literature:

2-naphthohydrazide; benzaldehyde; In N,N-dimethyl-formamide; at 60 ℃; Inert atmosphere;

With N-ethyl-N,N-diisopropylamine; eosin y; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Irradiation; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.02.022

Reference yield: 82.0%

benzoic acid hydrazide (613-94-5) + naphthalene-2-carboxylate (93-09-4) → 2-naphthalen-2-yl-5-phenyl-[1,3,4]oxadiazole (967-72-6)

Guidance literature:

With aluminum oxide; trichlorophosphate; Microwave irradiation;

DOI:10.1007/s00044-013-0588-2

upstream raw materials:

N-benzoyl-N'-[2]naphthoyl-hydrazine

2-Formyl-naphthalin-benzoylhydrazon

benzoic acid hydrazide

β-naphthaldehyde