1-Trimethylsilyl-1-butyne

Base Information

• Chemical Name: 1-Trimethylsilyl-1-butyne
• CAS No.: 62108-37-6
• Molecular Formula: C7H14Si
• Molecular Weight: 126.274
• Hs Code.: 2931900090
• Mol file: 62108-37-6.mol

Synonyms:1-Butynyltrimethylsilane;but-1-yn-1-yltrimethylsilane;1-TRIMETHYLSILYL-1-BUTYNE;Silane,1-butynyltrimethyl;trimethyl 1-butynylsilane;

Chemical Property of 1-Trimethylsilyl-1-butyne

Chemical Property:

• Vapor Pressure: 35.8mmHg at 25°C
• Boiling Point: 104.5°Cat760mmHg
• Flash Point: 6°C
• PSA: 0.00000
• Density: 0.774g/cm³
• LogP: 2.27720
• Storage Temp.: 2-8°C

Purity/Quality:

98%, ^*data from raw suppliers

but-1-yn-1-yltrimethylsilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Trimethylsilyl-1-butyne

There total 6 articles about 1-Trimethylsilyl-1-butyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.7%

chloro-trimethyl-silane (75-77-4) + but-1-ynyl-sodium (1001-57-6) → trimethyl 1-butynylsilane (62108-37-6)

Guidance literature:

With hydrogenchloride; In N-methyl-acetamide; 5,5-dimethyl-1,3-cyclohexadiene;

Reference yield: 75.0%

chloro-trimethyl-silane (75-77-4) + but-1-yne (107-00-6) → trimethyl 1-butynylsilane (62108-37-6)

Guidance literature:

but-1-yne; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1.5h; Inert atmosphere;

chloro-trimethyl-silane; In diethyl ether; hexane; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.12.077

Reference yield: 75.0%

methanesulfonic acid 3-trimethylsilyl-propyn-2-ynyl ester (71321-17-0) + methylmagnesium chloride (676-58-4) → trimethyl 1-butynylsilane (62108-37-6) + 1-methyl-1-(trimethylsilyl)allene (74542-82-8)

Guidance literature:

methylmagnesium chloride; With copper(I) bromide; lithium bromide; In tetrahydrofuran; at 0 ℃; Inert atmosphere;

methanesulfonic acid 3-trimethylsilyl-propyn-2-ynyl ester; In tetrahydrofuran; at -70 - 20 ℃; for 3.25h; Inert atmosphere;

DOI:10.15227/orgsyn.066.0001

upstream raw materials:

chloro-trimethyl-silane

but-1-yne

2-bromo-1-trimethylsiloxy-1-butene

but-1-ynyl-sodium

Downstream raw materials:

4-Ethyl-3-phenyl-5-(trimethylsilyl)pyridazin

(2-Ethyl-4-methylene-5,5-diphenyl-cyclopent-1-enyl)-trimethyl-silane

(2-Ethyl-4-methylene-3,3-diphenyl-cyclopent-1-enyl)-trimethyl-silane

phenyl threo-2,3-dimethyl-2-hydroxy-5-(trimethylsilyl)-4-pentynoate