4-(4-Phenyl-thiazol-2-ylamino)-phenol

Base Information

Chemical Name:4-(4-Phenyl-thiazol-2-ylamino)-phenol
CAS No.:3394-73-8
Molecular Formula:C₁₅H₁₂N₂OS
Molecular Weight:268.339
Hs Code.:
DSSTox Substance ID:DTXSID501287878
Pharos Ligand ID:VMGT1U5Y3MBZ
ChEMBL ID:CHEMBL562493

Synonyms:CHEMBL562493;Phenol, 4-[(4-phenyl-2-thiazolyl)amino]-;3394-73-8;4-(4-Phenyl-thiazol-2-ylamino)-phenol;Oprea1_063576;Oprea1_184264;SCHEMBL1822783;DTXSID501287878;KUC104643N;BDBM50293576;CCG-20343;KSC-1-275;4-(4-Phenylthiazol-2-ylamino)phenol;AKOS001665167;4-[(4-Phenyl-2-thiazolyl)amino]phenol;4131JH0380;AB00101215-01;SR-01000492463;SR-01000492463-1

Suppliers and Price of 4-(4-Phenyl-thiazol-2-ylamino)-phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(4-Phenyl-thiazol-2-ylamino)-phenol

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:268.06703418
Heavy Atom Count:19
Complexity:275

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CSC(=N2)NC3=CC=C(C=C3)O

Technology Process of 4-(4-Phenyl-thiazol-2-ylamino)-phenol

There total 6 articles about 4-(4-Phenyl-thiazol-2-ylamino)-phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1520-27-0
1-(4-hydroxyphenyl)thiourea

: 70-11-1
α-bromoacetophenone

: 3394-73-8
2-(4'-hydroxyphenyl)-amino-4-phenylthiazole

Guidance literature:: With Nafion-H; In water; ethylene glycol; at 50 ℃; for 0.333333h;
DOI:10.1080/17415993.2010.533773

Reference yield:

: 123-30-8
4-amino-phenol

: 5399-30-4
2-oxo-2-phenylethylthiocyanate

: 3394-73-8
2-(4'-hydroxyphenyl)-amino-4-phenylthiazole

Guidance literature:: With resorcin[4]arene cavitand glycoconjugate; In water; at 80 ℃; for 1h; Green chemistry;
DOI:10.1021/acs.joc.0c01150

Reference yield:

: 98-86-2
acetophenone

: 3394-73-8
2-(4'-hydroxyphenyl)-amino-4-phenylthiazole

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / chloroform / 2 h / 0 - 20 °C

2: ethanol / 0.5 h / 80 °C / Microwave irradiation

With bromine; In ethanol; chloroform; 2: |Hantzsch Thiazole Synthesis;
DOI:10.1016/j.ejmech.2014.07.025