3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate

Base Information

• Chemical Name: 3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate
• CAS No.: 1190206-06-4
• Molecular Formula: C₂₂H₃₄O₉S
• Molecular Weight: 474.573
• Mol file: 1190206-06-4.mol

Synonyms:3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate

Chemical Property of 3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate

Chemical Property:

Purity/Quality:

>98.00% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate

There total 3 articles about 3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

(2-(2-(2-(2-(2-(2-hydroxyethoxy)-ethoxy)-ethoxy)-ethoxy)-ethoxy)-ethyl) propargyl ether (944560-99-0) + p-toluenesulfonyl chloride (98-59-9) → 3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate (1190206-06-4)

Guidance literature:

With pyridine; dmap; at 20 ℃;

DOI:10.1021/jm900420c

Reference yield:

(2-(2-(2-(2-(2-(2-hydroxyethoxy)-ethoxy)-ethoxy)-ethoxy)-ethoxy)-ethyl) propargyl ether (944560-99-0) + Toluene-2-sulfonyl chloride (133-59-5) → 3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate (1190206-06-4)

Guidance literature:

Reference yield:

pentaethylene glycol (2615-15-8) → 3,6,9,12,15,18-hexaoxahenicos-20-yn-1-yl p-toluenesulfonate (1190206-06-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran

2: triethylamine / dichloromethane

With sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.3390/molecules27041163

upstream raw materials:

(2-(2-(2-(2-(2-(2-hydroxyethoxy)-ethoxy)-ethoxy)-ethoxy)-ethoxy)-ethyl) propargyl ether

p-toluenesulfonyl chloride

Toluene-2-sulfonyl chloride

pentaethylene glycol

Downstream raw materials:

ω-propynyl-3,6,9,12,15,18-hexaoxahenicos-1-amine