(3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate

Base Information

• Chemical Name: (3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate
• CAS No.: 1218923-25-1
• Molecular Formula: C₁₉H₂₂N₂O₅
• Molecular Weight: 358.394
• Mol file: 1218923-25-1.mol

Synonyms:(3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate

Chemical Property of (3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate

There total 3 articles about (3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-(3-(N-benzotriazolcarbonyloxy)(phenyl)(methyl)phenyl) propanoic acid benzotriazolide (1218923-24-0) + N-methoxylamine hydrochloride (593-56-6) → (3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate (1218923-25-1)

Guidance literature:

With triethylamine; In toluene; at 20 ℃; for 10h;

DOI:10.1016/j.ejmech.2010.04.008

Reference yield:

Dihydroketoprofen (59960-32-6) → (3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate (1218923-25-1)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / toluene / 1 h / 20 °C

2: triethylamine / toluene / 10 h / 20 °C

With triethylamine; In toluene;

DOI:10.1007/s00044-010-9309-2

Reference yield:

ketoprofen (22071-15-4,22161-86-0) → (3-(1-(methoxycarbamoyl)ethyl)phenyl)(phenyl)methyl methoxycarbamate (1218923-25-1)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium on activated charcoal; hydrogen / tetrahydrofuran

2: triethylamine / toluene / 1 h / 20 °C

3: triethylamine / toluene / 10 h / 20 °C

With palladium on activated charcoal; hydrogen; triethylamine; In tetrahydrofuran; toluene;

DOI:10.1007/s00044-010-9309-2

upstream raw materials:

2-(3-(N-benzotriazolcarbonyloxy)(phenyl)(methyl)phenyl) propanoic acid benzotriazolide

N-methoxylamine hydrochloride

ketoprofen

Dihydroketoprofen