5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene

Base Information

• Chemical Name: 5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene
• CAS No.: 83637-54-1
• Molecular Formula: C₁₇H₂₀O₂
• Molecular Weight: 256.345
• Mol file: 83637-54-1.mol

Synonyms:5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene

Chemical Property of 5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene

There total 7 articles about 5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

5-methoxy-1-<2-methyl-3-oxocyclohex-1-enyl(phenylsulphinyl)methyl>-1,2-dihydrocyclobutabenzene (83637-53-0) → 5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene (83637-54-1)

Guidance literature:

With acetic acid; zinc; for 1h; Ambient temperature;

Reference yield:

5-methoxybenzocyclobuten-1-yl toluene-p-sulphonate (30267-36-8) → 5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene (83637-54-1)

Guidance literature:

Multi-step reaction with 5 steps

1: dimethylformamide

2: m-chloroperbenzoic acid / CH₂Cl₂

3: 38 percent / lithium di-isopropylamide / tetrahydrofuran

4: pyridinium chlorochromate / CH₂Cl₂

5: zinc / acetic acid

With 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; zinc; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; acetic acid; N,N-dimethyl-formamide;

DOI:10.1039/c39820000699

Reference yield:

5-methoxybenzocyclobut-1-enylmethyl phenyl sulphoxide (83637-51-8) → 5-methoxy-1-(2-methyl-3-oxocyclohex-1-enylmethyl)-1,2-dihydrocyclobutabenzene (83637-54-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 38 percent / lithium di-isopropylamide / tetrahydrofuran

2: pyridinium chlorochromate / CH₂Cl₂

3: zinc / acetic acid

With pyridinium chlorochromate; zinc; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; acetic acid;

DOI:10.1039/c39820000699

upstream raw materials:

5-methoxy-1-<2-methyl-3-oxocyclohex-1-enyl(phenylsulphinyl)methyl>-1,2-dihydrocyclobutabenzene

2-methyl-2-cyclohexen-1-one

5-methoxybenzocyclobuten-1-yl toluene-p-sulphonate

5-methoxybenzocyclobut-1-enyl phenyl sulphide

Downstream raw materials:

1-(4-hydroxymethylene-2-methyl-3-oxocyclohexylmethyl)-5-methoxy-1,2-dihydrocyclobutabenzene

5-methoxy-1-(2-methyl-3-oxo-4-phenylthiomethylenecyclohexylmethyl)-1,2-dihydrocyclobutabenzene

Methanesulfonic acid 4-(4-methoxy-bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ylmethyl)-3-methyl-2-oxo-cyclohex-(E)-ylidenemethyl ester

3-methoxy-7-methyl-4bα,5,6,8a,9,10-hexahydro-6α,8aα-ethanophenanthren-8(7H)-one toluene-p-sulphonylhydrazone