N-(3-oxo-2-propyl-2,3-dihydroisoquinolin-4-yl)-N-(4-(trifluoromethyl)phenyl)picolinamide

Base Information

Chemical Name:N-(3-oxo-2-propyl-2,3-dihydroisoquinolin-4-yl)-N-(4-(trifluoromethyl)phenyl)picolinamide
CAS No.:1426687-67-3
Molecular Formula:C₂₅H₂₀F₃N₃O₂
Molecular Weight:451.448
Hs Code.:

Synonyms:N-(3-oxo-2-propyl-2,3-dihydroisoquinolin-4-yl)-N-(4-(trifluoromethyl)phenyl)picolinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(3-oxo-2-propyl-2,3-dihydroisoquinolin-4-yl)-N-(4-(trifluoromethyl)phenyl)picolinamide

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Technology Process of N-(3-oxo-2-propyl-2,3-dihydroisoquinolin-4-yl)-N-(4-(trifluoromethyl)phenyl)picolinamide

There total 1 articles about N-(3-oxo-2-propyl-2,3-dihydroisoquinolin-4-yl)-N-(4-(trifluoromethyl)phenyl)picolinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 98-98-6
2-Picolinic acid

: 455-14-1
4-trifluoromethylphenylamine

: 627-36-1
n-propyl isocyanide

: 59259-01-7
2-<2-(1,3-dioxolanyl)>benzaldehyde

: 1426687-67-3
N-(3-oxo-2-propyl-2,3-dihydroisoquinolin-4-yl)-N-(4-(trifluoromethyl)phenyl)picolinamide

Guidance literature:: 2-Picolinic acid; 4-trifluoromethylphenylamine; n-propyl isocyanide; 2-<2-(1,3-dioxolanyl)>benzaldehyde; In methanol; at 20 ℃; for 12h; Inert atmosphere;

With perchloric acid; In water; acetonitrile; at 20 ℃; for 8h; Inert atmosphere;
DOI:10.1021/co400001h