6-aminopenicillanic acid

Base Information

• Chemical Name: 6-aminopenicillanic acid
• CAS No.: 21794-93-4
• Molecular Formula: C₈H₁₂N₂O₃S
• Molecular Weight: 216.261
• Mol file: 21794-93-4.mol

Synonyms:6-aminopenicillanic acid

Chemical Property of 6-aminopenicillanic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-aminopenicillanic acid

There total 12 articles about 6-aminopenicillanic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.5%

→ 6-[D(-)-α-(4-ethyl-2,3-dioxo-1-piperazinocarbonylamino)-p-hydroxyphenylacetamido]penicillanic acid + 6-aminopenicillanic acid (551-16-6,1079-37-4,3115-55-7,21794-93-4,145920-51-0)

Guidance literature:

Reference yield:

Penicillin G potassium (113-98-4) → 6-aminopenicillanic acid (551-16-6,1079-37-4,3115-55-7,21794-93-4,145920-51-0)

Guidance literature:

With sodium hydroxide; In water;

Reference yield:

Penicillin G potassium (113-98-4) + thioacetamide (62-55-5) + chlorothio-trichloro-methane (594-42-3) + dimethylsilicon dichloride (75-78-5,30107-43-8) → 6-aminopenicillanic acid (551-16-6,1079-37-4,3115-55-7,21794-93-4,145920-51-0)

Guidance literature:

With phosphorus pentachloride; ammonia; In methanol; dichloromethane; water; N,N-dimethyl-aniline;

upstream raw materials:

benzylpenicillin

penicillin G

Penicillin G potassium

thioacetamide

Downstream raw materials:

6ξ-[(N-phenyl-glycyl)-amino]-penicillanic acid

penicillin G

N-Salicylidene-6-aminopenicillanic Acid Sulfoxide

Refernces

• 1、 -. "Deacylation of amides". . . Retrieved 2008/06/13.
• 2、 -. "β-Lactam antibiotic esterification process using methoxymethyl methane sulfonate". . . Retrieved 2008/06/13.