2-(4-methoxyphenyl)-1-indanone oxime methyl ether

Base Information

• Chemical Name: 2-(4-methoxyphenyl)-1-indanone oxime methyl ether
• CAS No.: 145962-42-1
• Molecular Formula: C₁₇H₁₇NO₂
• Molecular Weight: 267.327
• Mol file: 145962-42-1.mol

Synonyms:2-(4-methoxyphenyl)-1-indanone oxime methyl ether

Chemical Property of 2-(4-methoxyphenyl)-1-indanone oxime methyl ether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-(4-methoxyphenyl)-1-indanone oxime methyl ether

There total 7 articles about 2-(4-methoxyphenyl)-1-indanone oxime methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(4-methoxyphenyl)-2,3-dihydro-1H-inden-1-one (1086-43-7) + N-methoxylamine hydrochloride (593-56-6) → 2-(4-methoxyphenyl)-1-indanone oxime methyl ether (145962-42-1)

Guidance literature:

With sodium acetate; In methanol; Ambient temperature;

DOI:10.1021/jm950833d

Reference yield:

(±)-2-(4-methoxyphenyl)-3-phenylpropanoic acid (1769-85-3) → 2-(4-methoxyphenyl)-1-indanone oxime methyl ether (145962-42-1)

Guidance literature:

Multi-step reaction with 3 steps

1: (COCl)2, DMF / CH₂Cl₂ / 1 h / Ambient temperature

2: AlCl₃ / CH₂Cl₂ / 0.25 h / 0 °C

3: 100 percent / NaOAc / methanol / Ambient temperature

With aluminium trichloride; oxalyl dichloride; sodium acetate; N,N-dimethyl-formamide; In methanol; dichloromethane;

DOI:10.1021/jm950833d

Reference yield:

3-Phenyl-2-<4-methoxy-phenyl>-propionsaeure-chlorid (39104-22-8) → 2-(4-methoxyphenyl)-1-indanone oxime methyl ether (145962-42-1)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / CH₂Cl₂ / 0.25 h / 0 °C

2: 100 percent / NaOAc / methanol / Ambient temperature

With aluminium trichloride; sodium acetate; In methanol; dichloromethane;

DOI:10.1021/jm950833d

upstream raw materials:

2-(4-methoxyphenyl)-2,3-dihydro-1H-inden-1-one

N-methoxylamine hydrochloride

(±)-2-(4-methoxyphenyl)-3-phenylpropanoic acid

3-Phenyl-2-<4-methoxy-phenyl>-propionsaeure-chlorid

Downstream raw materials:

2-(4-methoxyphenyl)indanamine

Refernces