Tyrphostin A1

Base Information

Chemical Name:Tyrphostin A1
CAS No.:2826-26-8
Molecular Formula:C11H8 N2 O
Molecular Weight:184.197
Hs Code.:2926909090
European Community (EC) Number:808-183-6
NSC Number:637326,1343
DSSTox Substance ID:DTXSID10182508
Nikkaji Number:J305.964B
Wikidata:Q27074343
NCI Thesaurus Code:C2035
Pharos Ligand ID:A8AJF88B7VDX
ChEMBL ID:CHEMBL77456
Mol file:2826-26-8.mol

Synonyms:(3,4-dihydroxybenzylidene)malononitrile;(3,4-dihydroxyphenyl)methylene propanedinitrile;3,4-dihydroxybenzylidenemalononitrile;RG 50810;RG-50810;tyrphostin 23;tyrphostin A1;tyrphostin A23;tyrphostin AG18;tyrphostin RG50810

Suppliers and Price of Tyrphostin A1

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Tyrphostin A1
50mg
$ 200.00

TCI Chemical
Tyrphostin A1 >98.0%(GC)
1g
$ 780.00

TCI Chemical
Tyrphostin A1 >98.0%(GC)
200mg
$ 224.00

Sigma-Aldrich
Tyrphostin 1 ≥98%
25mg
$ 188.00

Matrix Scientific
2-[(4-Methoxyphenyl)methylene]propanedinitrile
1g
$ 150.00

Crysdot
Tyrphostin A1 98+%
100mg
$ 141.00

Crysdot
Tyrphostin A1 98+%
10mg
$ 46.00

ChemScene
Tyrphostin A1 99.50%
10mg
$ 79.00

ChemScene
Tyrphostin A1 99.50%
100mg
$ 242.00

Chem-Impex
TyrphostinA1,≥98%(GC)Hazmat ≥98%(GC)
1G
$ 980.76

Total 19 raw suppliers

Chemical Property of Tyrphostin A1

Chemical Property:

Vapor Pressure:3.85E-05mmHg at 25°C
Melting Point:113-116oC(lit.)
Boiling Point:352.4°Cat760mmHg
Flash Point:148.8°C
PSA：56.81000
Density:1.169g/cm³
LogP:2.12576
Storage Temp.:2-8°C
Sensitive.:Light Sensitive
Solubility.:chloroform: soluble50mg/mL, clear, light yellow
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:184.063662883
Heavy Atom Count:14
Complexity:289

Purity/Quality:

99%, ^*data from raw suppliers

Tyrphostin A1 ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22
Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=C(C#N)C#N
Uses Tyrphostin A1 is an inactive Tyrphostin used as a negative control for Tyrphostin A23.

Technology Process of Tyrphostin A1

There total 50 articles about Tyrphostin A1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 123-11-5
4-methoxy-benzaldehyde

: 109-77-3
malononitrile

: 2826-26-8
2-(4-methoxyphenylmethylene)malononitrile

Guidance literature:: With third generation polystyrene supported poly(amidoamine) dendrimer; In ethanol; at 30 ℃; for 0.25h;
DOI:10.1002/ejoc.200800516

Reference yield: 95.0%

: 2186-92-7
p-Anisaldehyde dimethyl acetal

: 109-77-3
malononitrile

: 2826-26-8
2-(4-methoxyphenylmethylene)malononitrile

Guidance literature:: In ethyl acetate; at 50 ℃;

Reference yield: 90.0%

: 105-13-5
4-Methoxybenzyl alcohol

: 109-77-3
malononitrile

: 2826-26-8
2-(4-methoxyphenylmethylene)malononitrile

Guidance literature:: With Ni nanoparticle immobilized-sulfonated imidazolium-based ionic liquid-functionalized magnetic silica nanoparticles; air; In water; for 1h; Heating;
DOI:10.1002/aoc.4452