Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester

Base Information

Chemical Name:Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester
CAS No.:602319-20-0
Molecular Formula:C₂₂H₂₅NO₆
Molecular Weight:399.444
Hs Code.:

Synonyms:Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester

Suppliers and Price of Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester

There total 1 articles about Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-88-4
benzoyl chloride

: 62023-65-8,76498-21-0,77171-41-6,82848-28-0,105181-72-4,116661-86-0
(2S,3S)-3-tert-butoxycarbonylamino-2-hydroxy-4-phenylbutanoic acid

: 602319-20-0
Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester

Guidance literature:: With pyridine; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1021/jm034112n

Reference yield:

: 108-93-0
cyclohexanol

: 602319-20-0
Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester

: 602319-14-2
(1S,2S)-2-[(tert-butoxycarbonyl)amino]-1-[(cyclohexyloxy)carbonyl]-3-phenylpropyl benzoate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;
DOI:10.1021/jm034112n

Reference yield:

: 602319-20-0
Benzoic acid (1S,2S)-2-tert-butoxycarbonylamino-1-carboxy-3-phenyl-propyl ester

: (1S,2S)-2-amino-1-[(cyclohexyloxy)carbonyl]-3-phenylpropyl benzoate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 190 mg / DMAP; EDC*HCl / CH₂Cl₂ / 20 °C

2: 100 percent / HCl; anisole / dioxane / 1 h / 20 °C

With hydrogenchloride; dmap; methoxybenzene; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jm034112n