6-Chlor-2-dimethylamino-4-phenylchinolin

Base Information

• Chemical Name: 6-Chlor-2-dimethylamino-4-phenylchinolin
• CAS No.: 31576-98-4
• Molecular Formula: C₁₇H₁₅ClN₂
• Molecular Weight: 282.772
• Mol file: 31576-98-4.mol

Synonyms:6-Chlor-2-dimethylamino-4-phenylchinolin

Chemical Property of 6-Chlor-2-dimethylamino-4-phenylchinolin

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-Chlor-2-dimethylamino-4-phenylchinolin

There total 8 articles about 6-Chlor-2-dimethylamino-4-phenylchinolin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N,N-dimethylacetamide dimethyl acetal (18871-66-4) → 6-Chlor-2-dimethylamino-4-phenylchinolin (31576-98-4)

Guidance literature:

In ethanol; for 24h; Heating;

DOI:10.1002/ardp.19863190409

Reference yield: 75.0%

Thiram (137-26-8,93196-73-7) + 1-phenyl-1-(2-amino-5-chlorophenyl)ethylene (3158-99-4) → 6-Chlor-2-dimethylamino-4-phenylchinolin (31576-98-4)

Guidance literature:

With iodine; copper(II) bis(trifluoromethanesulfonate); In chlorobenzene; at 120 ℃; for 12h; Inert atmosphere;

DOI:10.1055/a-1735-6250

Reference yield: 47.0%

2,6-dichloro-4-phenylquinoline (10352-30-4) + dimethyl amine (124-40-3) → 6-Chlor-2-dimethylamino-4-phenylchinolin (31576-98-4)

Guidance literature:

In ethanol; at 130 ℃; for 9h; sealed tube;

DOI:10.1248/cpb.28.2618

upstream raw materials:

2,6-dichloro-4-phenylquinoline

dimethyl amine

N,N-dimethylacetamide dimethyl acetal

N-(2-benzoyl-4-chlorophenyl)acetamide

Downstream raw materials:

6-Chlor-1,2-dihydro-4-phenylchinolin-2-on

7-Chlor-5-phenyltetrazolo<1,5-a>chinolin