7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone

Base Information

Chemical Name:7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone
CAS No.:957110-14-4
Molecular Formula:C₂₀H₁₆F₃N₃O₈S
Molecular Weight:515.424
Hs Code.:

Synonyms:7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone

Suppliers and Price of 7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone

There total 8 articles about 7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 957110-13-3
7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2(1H)-quinolinone

: 358-23-6
trifluoromethylsulfonic anhydride

: 957110-14-4
7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone

Guidance literature:: With triethylamine; at -20 ℃; for 0.5h;
DOI:10.1021/jo7017813

Reference yield:

: 1568-70-3
4-methoxy-2-nitrophenol

: 957110-14-4
7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone

Guidance literature:: Multi-step reaction with 8 steps

1: 21 g / glacial acetic acid; nitric acid / 15 - 30 °C

2: 99 percent / diethyl ether

3: cyclohexene / palladium on carbon / ethanol / 0.25 h / Heating

4: 6.5 g / acetic acid / 0.08 h / Heating

5: cyclohexene / palladium on carbon / ethanol / 24 h / Heating

6: 21 g / xylene / 2 h / 160 - 180 °C

7: 52 percent / polyphosphoric acid / 5 h / 75 °C

8: 70 percent / triethylamine / 0.5 h / -20 °C

With PPA; nitric acid; acetic acid; triethylamine; cyclohexene; palladium on activated charcoal; In diethyl ether; ethanol; xylene; 7: Knorr cyclization;
DOI:10.1021/jo7017813

Reference yield:

: 3410-94-4
4-methoxy-2,6-dinitrophenol

: 957110-14-4
7-acetamido-5,8-dimethoxy-4-(2-nitrophenyl)-2-(trifluoromethanesulfonyloxy)quinolinone

Guidance literature:: Multi-step reaction with 7 steps

1: 99 percent / diethyl ether

2: cyclohexene / palladium on carbon / ethanol / 0.25 h / Heating

3: 6.5 g / acetic acid / 0.08 h / Heating

4: cyclohexene / palladium on carbon / ethanol / 24 h / Heating

5: 21 g / xylene / 2 h / 160 - 180 °C

6: 52 percent / polyphosphoric acid / 5 h / 75 °C

7: 70 percent / triethylamine / 0.5 h / -20 °C

With PPA; acetic acid; triethylamine; cyclohexene; palladium on activated charcoal; In diethyl ether; ethanol; xylene; 6: Knorr cyclization;
DOI:10.1021/jo7017813