Dichloro(ethylenediamine)platinum(II)

Base Information

• Chemical Name: Dichloro(ethylenediamine)platinum(II)
• CAS No.: 14096-51-6
• Molecular Formula: C2H8 Cl2 N2 Pt
• Molecular Weight: 326.085
• European Community (EC) Number: 237-943-4
• Mol file: 14096-51-6.mol

Synonyms:cis-dichloro(ethylenediamine)platinum II;dichloro(1,2-ethanediamine-N,N')platinum;ethylenediamine platinum dichloride;platinum ethylenediamine dichloride;PtCl2(ethane-1,2-diamine)

Chemical Property of Dichloro(ethylenediamine)platinum(II)

Chemical Property:

• Vapor Pressure: 15.8mmHg at 25°C
• Boiling Point: 119.7°Cat760mmHg
• Flash Point: 33.9°C
• PSA: 52.04000
• Density: g/cm³
• LogP: 1.68090
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Hygroscopic
• Water Solubility.: Soluble in water.
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 324.971248
• Heavy Atom Count: 7
• Complexity: 8.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dichloro(ethylenediamine)platinum(II) 99% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CN)N.Cl[Pt]Cl
• Uses: It is also used as a reactant for Electro reduction reactions.

Technology Process of Dichloro(ethylenediamine)platinum(II)

There total 58 articles about Dichloro(ethylenediamine)platinum(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

potassium tetrachloroplatinate(II) (10025-99-7) + ethylenediamine (107-15-3,85404-18-8) → dichloro(ethylenediamine)platinum(II) (14096-51-6)

Guidance literature:

In water; by a react. of a 1:1 mixt. of a ligand with Pt-contg. compd. in water overnight;

DOI:10.1039/b212553f

Reference yield: 90.0%

potassium tetrachloroplatinate(II) (10025-99-7) + ethylenediamine hydrochloride (18299-54-2) → dichloro(ethylenediamine)platinum(II) (14096-51-6)

Guidance literature:

In solid; byproducts: KCl, HCl; thoroughly grinding of mixt.; heating (long narrow glass test tube, electric furnace), 240-250 °C, 120 min; cooling to room temp.; washing on a filter; isomeric purity; elem. anal.;

Reference yield: 82.0%

cis-(ethylenediamine)diiodoplatinum(II) (23858-10-8) + silver nitrate + sodium chloride (7647-14-5) → dichloro(ethylenediamine)platinum(II) (14096-51-6)

Guidance literature:

In water; byproducts: AgI; addn. of soln. of AgNO3 to suspn. of complex, stirring (50°C, 1 h), filtration, addn. of tenfold excess of NaCl, heating (0.5 h); cooling (4°C), filtration, washing (ice-cold H2O, EtOH, ether);

DOI:10.1071/CH9950793

upstream raw materials:

ethylenediamine platinum(II) nitrate

{Pten₂}{PtCl₄}

ethylenediamine

potassium tetrachloroplatinate(II)

Downstream raw materials:

{PtenCl₄}

(1,2-diaminoethane)(diaqua)platinum(II) dinitrate

(OC-6-33)-dichlorido(ethane-1,2-diamine)dihydroxidoplatinum(IV)

{Pta₂en}Cl₂

Refernces

• 1、 Chen, Catherine K. J.,Zhang, Jenny Z.,Aitken, Jade B.,Hambley, Trevor W.. "Influence of equatorial and axial carboxylato ligands on the kinetic inertness of platinum(IV) complexes in the presence of ascorbate and cysteine and within dld-1 cancer cells". . p. 8757 - 8764. Retrieved 2013.
• 2、 Rajkovi?, Sne?ana,A?anin, Darko P.,?ivkovi?, Marija D.,Djuran, Milo? I.. "Synthesis of different pyrazine-bridged platinum(II) complexes and 1H NMR study of their catalytic abilities in the hydrolysis of the N-acetylated l-methionylglycine". . p. 42 - 47. Retrieved 2013.
• 3、 Sutton, Emily C.,Mcdevitt, Christine E.,Prochnau, Jack Y.,Yglesias, Matthew V.,Mroz, Austin M.,Yang, Min Chieh,Cunningham, Rachael M.,Hendon, Christopher H.,Derose, Victoria J.. "Nucleolar Stress Induction by Oxaliplatin and Derivatives". . p. 18411 - 18415. Retrieved 2019.
• 4、 Zhou, Qian,You, Chaoqun,Ling, Yang,Wu, Hongshuai,Sun, Baiwang. "pH and thermo dual stimulus-responsive liposome nanoparticles for targeted delivery of platinum-acridine hybrid agent". . p. 41 - 48. Retrieved 2019.
• 5、 Josephsen, Jens. "Diaminehalogenoplatinum(II) complex reactions with DMSO". . p. 54 - 58. Retrieved 2018.
• 6、 Devoto, G.,Massacesi, M.,Ponticelli, G.,Medda, R.,Floris, G.. "". . p. 1023 - 1026. Retrieved 1986.
• 7、 Bisi-Castellani, Carla,Maresca, Luciana,Natile, Giovanni. "". . p. 157 - 162. Retrieved 1984.
• 8、 Fanizzi, Francesco P.,Natile, Giovanni,Maresca, Luciana,Manotti-Lanfredi, Anna M.,Tiripicchio, Antonio. "Platinum(IV) Complexes containing a Cationic Amine Ligand: Crystal Structure of pentachloroplatinum(IV) Monohydrate". . p. 1467 - 1470. Retrieved 1984.
• 9、 Vasi?, Ivana,Rajkovi?, Sne?ana,Arsenijevi?, Aleksandar,Milovanovi?, Marija,Arsenijevi?, Neboj?a,Milovanovi?, Jelena,?ivkovi?, Marija D.. "In vitro and in vivoactivity of series of cationic dinuclearPt(II) complexes". . . Retrieved 2021/10/01.