Benzamide, N-acetyl- (6CI,7CI,8CI,9CI)

Base Information

• Chemical Name: Benzamide, N-acetyl- (6CI,7CI,8CI,9CI)
• CAS No.: 1575-95-7
• Molecular Formula: C9H9 N O2
• Molecular Weight: 163.176
• Hs Code.: 2925190090
• Mol file: 1575-95-7.mol

Synonyms:N-Acetylbenzamide;NSC 85835

Chemical Property of Benzamide, N-acetyl- (6CI,7CI,8CI,9CI)

Chemical Property:

• Vapor Pressure: 0.000523mmHg at 25°C
• Melting Point: 117 °C
• Boiling Point: 312.6°Cat760mmHg
• PKA: 10.55±0.46(Predicted)
• Flash Point: 142.6°C
• PSA: 46.17000
• Density: 1.137g/cm³
• LogP: 1.35380

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzamide, N-acetyl- (6CI,7CI,8CI,9CI)

There total 95 articles about Benzamide, N-acetyl- (6CI,7CI,8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

acetic acid (64-19-7,77671-22-8) + benzonitrile (100-47-0) → N-acetylbenzamide (1575-95-7) + benzamide (55-21-0,27208-38-4)

Guidance literature:

With iron(II) chloride; at 130 ℃; for 24h; Product distribution; other temperature; other reaction time;

Reference yield: 81.0%

N-(phenylmethyl)acetamide (588-46-5) → N-acetylbenzamide (1575-95-7) + benzaldehyde (100-52-7)

Guidance literature:

With pyridine; Py-NHPI; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; cobalt hexafluorophosphate; at 65 ℃; for 24h; under 760 Torr;

DOI:10.1016/j.tetlet.2005.04.136

Reference yield: 81.0%

n-butylammonium acetate (1641-36-7) + benzonitrile (100-47-0) → N-acetylbenzamide (1575-95-7) + benzamide (55-21-0,27208-38-4)

Guidance literature:

n-butylammonium acetate; With trifluoromethylsulfonic anhydride; at 0 - 20 ℃; for 0.0833333h;

benzonitrile; at 60 ℃; for 1h;

With water; sodium hydrogencarbonate;

DOI:10.1016/j.tetlet.2012.03.121

upstream raw materials:

acetic anhydride

sodium benzamidate

benzamide

acetic acid

Downstream raw materials:

N-acetylacetamide

N-benzoylbenzamide

benzoic acid ethyl ester

ethyl acetate